NMDAR

作品数：265被引量：758H指数：12
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相关作者：孙莉高明奇王亚娟陈春美姜玉武更多>>
相关机构：中南大学中国医科大学福建医科大学南京医科大学更多>>
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A New Potential Strategy for Treatment of Ischemic Stroke:Targeting TRPM2–NMDAR Association被引量：2
《Neuroscience Bulletin》2023年第4期703-706,共4页Jiayun Xu Wei Zhang Jianhong Dong Liying Cao Zhihui Huang 
supported by grants from the Research Start-up Project by Hangzhou Normal University(4125C5021920435 and 4125C5021920453).
Ischemic stroke accounts for~85%of all strokes and generally occurs when blood flow is severely reduced due to clots or masses blocking blood vessels and cutting off blood flow to brain cells.The death or damage to ne...
关键词：ISCHEMIC PARALYSIS damage 
A Critical Role for γCaMKII in Decoding NMDA Signaling to Regulate AMPA Receptors in Putative Inhibitory Interneurons被引量：1
《Neuroscience Bulletin》2022年第8期916-926,共11页Xingzhi He Yang Wang Guangjun Zhou Jing Yang Jiarui Li Tao Li Hailan Hu Huan Ma 
This work was supported by Science and Technology Innovation 2030-Major Project(2021ZD0203501);the National Natural Science Foundation of China(81930030,31771109,and 31722023);the National Key R&D Program of China(2019YFA0508603);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-057);Project for Hangzhou Medical Disciplines of Excellence;Key Project for Hangzhou Medical Disciplines;the Fundamental Research Funds for the Central Universities of China(2018XZZX002-02,2019XZZX001-01-04,and 2019FZA7009);the National Postdoctoral Program for Innovative Talents(BX2021263).
CaMKII is essential for long-term potentiation(LTP),a process in which synaptic strength is increased following the acquisition of information.Among the four CaMKII isoforms,γCaMKII is the one that mediates the LTP o...
关键词：Synaptic plasticity LTP Inhibitory interneurons γCaMKII AMPAR NMDAR 
On the Eve of Upgrading Antidepressants:(R)-Ketamine and Its Metabolites被引量：5
《Neuroscience Bulletin》2016年第6期565-568,共4页Kai Yuan Ying Han Kenji Hashimoto Lin Lu 
Ketamine is a noncompetitive N-methyl-D-aspartate receptor （NMDAR） antagonist that has attracted wide- spread attention for its rapid-onset antidepressant effects, especially in individuals with treatment-resistant ...
关键词：NMDAR Ketamine and Its Metabolites On the Eve of Upgrading Antidepressants 
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