PARALYSIS

作品数:232被引量:320H指数:7
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相关领域:医药卫生更多>>
相关作者:李健东高志强徐文尹金淑刘稳更多>>
相关机构:北京世纪坛医院安徽职业技术学院安徽师范大学北京协和医院更多>>
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相关基金:国家自然科学基金浙江省自然科学基金瑞士科学基金国家现代农业产业技术体系建设项目更多>>
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  • 期刊=Neural Regeneration Researchx
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Spinal cord injury regenerative therapy development:integration of design of experiments
《Neural Regeneration Research》2025年第9期2571-2573,共3页Yuji Okano Hideyuki Okano Yoshitaka Kase 
supported by the Keio University Medical Science Fund(to YO);the General Insurance Association of Japan(to YK);the Takeda Science Foundation(to YK);grants from the Japan Agency for Medical Research and Development(AMED)(Grant JP24bm1123037 and JP24ym0126118)(to HO)。
Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers con...
关键词:SPINAL PARALYSIS INJURY 
Disruption of neuronal actin barrier promotes the entry of disease-implicated proteins to exacerbate amyotrophic lateral sclerosis pathology
《Neural Regeneration Research》2025年第9期2589-2590,共2页Mikio Shimizu Tatsusada Okuno 
supported in port by the JSPS KAKENHI(grant number 22K07539 to MS);funded by Mitsubishi Tanabe Pharma Corporation。
Amyotrophic lateral sclerosis(ALS)is a devastating neurological disease characterized by the accumulation of aberrant proteins in motor neurons of the brain and spinal cord.Patients with ALS develop skeletal muscle we...
关键词:PARALYSIS SCLEROSIS 
Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis
《Neural Regeneration Research》2025年第8期2319-2320,共2页Kiyoung Kim 
supported by the BK21 FOUR(Fostering Outstanding Universities for Research);the Basic Science Research Program through the National Research Foundation of Korea(NRF);the Regional Innovation Mega Project Program through the Korea Innovation Foundation funded by the Ministry of Education(MOE);the Ministry of Science and ICT(MSIT)(NRF-2022R1A2C1004204,RS-2023-00219563,2023-DD-UP-0007);the Soonchunhyang University Research Fund(to KK)。
Amyotrophic lateral sclerosis(ALS),also known as Lou Geh rig's disease,is a progressive neurodegenerative disorder that affects motor neurons in the brain and spinal cord.This leads to muscle weakness,paralysis,and ul...
关键词:PARALYSIS SCLEROSIS RESPIRATORY 
Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures
《Neural Regeneration Research》2025年第1期265-276,共12页Yao Yuan Lingqi Yu Xudong Zhuang Dongjing Wen Jin He Jingmei Hong Jiayu Xie Shengan Ling Xiaoyue Du Wenfeng Chen Xinrui Wang 
supported by the Natural Science Foundation of Fujian Province,No.2020J02027;the National Natural Science Foundation of China,No.31970461;the Foundation of NHC Key Laboratory of Technical Evaluation of Fertility Regulation for Non-human Primate,Fujian Maternity and Child Health Hospital,No.2022-NHP-05(all to WC).
Certain amino acids changes in the human Na^(+)/K^(+)-ATPase pump,ATPase Na^(+)/K^(+)transporting subunit alpha 1(ATP1A1),cause Charcot-Marie-Tooth disease type 2(CMT2)disease and refractory seizures.To develop in viv...
关键词:ATP1A1 Atpα bang-sensitive paralysis Charcot-Marie-Tooth disease type 2 CRISPR/Cas9 homology-directed repair Na^(+)/K^(+)-ATPase point mutation seizures sodium pump 
Lin28 as a therapeutic target for central nervous system regeneration and repair
《Neural Regeneration Research》2024年第2期397-398,共2页Shuo Wang Shuxin Li 
Axon disconnection in the central nervous system(CNS) usually causes signal transduction failure and severe functional deficits in patients with neurological disorders. Currently, there is no cure for patients with CN...
关键词:PARALYSIS THERAPEUTIC SYSTEM 
Amyotrophic lateral sclerosis disease burden:doing better at getting better被引量:2
《Neural Regeneration Research》2023年第8期1728-1729,共2页Cinzia Volonté Susanna Amadio 
supported by FATALSDRUG Project(Progetti di Ricerca@CNR)from National Research Council,Italy(to CV)。
Amyotrophic lateral sclerosis(ALS)is classified as a multigenic,multifactorial,and heterogeneous neurodegenerative/neuroinflammatory disease that slays especially upper and lower motor neurons controlling voluntary mu...
关键词:SCLEROSIS PARALYSIS RESPIRATORY 
Inhibition of central axon regeneration: perspective from chondroitin sulfate proteoglycans in lamprey spinal cord injury被引量:1
《Neural Regeneration Research》2022年第9期1955-1956,共2页Jianli Hu Li-Qing Jin Michael E.Selzer 
Background:Failure of axon regeneration after spinal cord injury(SCI)underlies the paralysis that so profoundly affects patients’quality of life.Many factors are involved in the regeneration failure.Chondroitin sulfa...
关键词:PARALYSIS INJURY LEUKOCYTE 
Glial cell line-derived neurotrophic factor in brain repair after focal ischemic stroke被引量:1
《Neural Regeneration Research》2022年第8期1735-1736,共2页Zhe Zhang Nannan Zhang Shinghua Ding 
supported by the National Institute of Health grants R01NS069726 and R01NS094539 to SD;the America Heart Association grants 16GRNT31280014 to SD.
Cerebral focal ischemic stroke(FIS)is a leading brain disorder associated with human debilitation and death.It is induced by the formation of a thrombus in the arteries that supply blood to the central nervous system....
关键词:PARALYSIS ARTERIES suddenly 
Neuronal and endothelial transglutaminase-2 expression in experimental autoimmune encephalomyelitis and multiple sclerosis
《Neural Regeneration Research》2022年第7期1471-1472,共2页Damien D.Pearse Mousumi Ghosh 
supported by The John M.and Jocelyn H.K.Watkins Distinguished Chair in Cell Therapies(to DDP);The Miami Project to Cure Paralysis and The Buoniconti Fund(to DDP and MG)。
Multiple sclerosis(MS)is a neurological condition characterized by the disruption of the blood-brain barrier,immune system activation,and infla mmation that is accompanied by glial reactivity,neuronal cell death,axon ...
关键词:SCLEROSIS PARALYSIS AUTOIMMUNE 
Targeting the motor cortex to restore walking after incomplete spinal cord injury被引量:1
《Neural Regeneration Research》2022年第7期1489-1490,共2页Marina Martinez 
supported by the Craig H.Neilsen Foundation;the Natural Sciences and Engineering Research Council of Canada;the Canadian Institutes of Health Research(to MM);supported by a salary award from Fonds de Recherche Québec-Santé。
Spinal cord injury(SCI),second only to stroke,is the leading cause of paralysis.The ability to walk is often lost after SCI,reducing independence and quality of life.Restoration of walking is cited as a priority among...
关键词:INCOMPLETE PARALYSIS INJURY 
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