Renin-angiotensin-aldosterone system(RAAS)blockade is often the first-line medication for treating pediatric and adult patients with hypertension,especially those with preexisting chronic kidney disease(CKD)[1,2].Howe...
Background Off-label and unlicensed prescriptions pose a severe safety concern among the pediatric population.We aimed to summarize the up-to-date evidence on the extent,reasons,and consequences of off-label and unlic...
Background In the past two decades, many legislative and regulatory initiatives were taken globally to improve drug use in children. However, children are still found to be prescribed with off-label drugs. This study ...