ALDOSTERONE

作品数：95被引量：201H指数：7
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Association of renin-angiotensin-aldosterone blockade and hypotension after carotid artery stenting
《Chinese Medical Journal》2024年第22期2764-2766,共3页Le Cao Xuening Zhang Shu Yang Hang Wang Yunfei An William Robert Kwapong Jincheng Wan Nengwei Yu Ping Wang Fayun Hu Bo Wu 
supported by grants from the National Natural Science Foundation of China(Nos.82071320,8601022);Sichuan Science and Technology Program(No.2023NSFSC1558);Medical-Engineering Integration Interdisciplinary Talent Training Fund Project of West China Hospital,Sichuan University and University of Electronic Science and Technology of China(No.HXDZ22011/ZYGX2022YGRH017).
To the Editor:Carotid artery stenting(CAS)is a key treatment of extracranial internal carotid artery(EICA)stenosis for secondary stroke prevention.Hypotension is a common perioperative event concerning balloon dilatio...
关键词：CAROTID BALLOON artery 
Prevalence and impact of diabetes and prediabetes on presentation and complications of primary hyperaldosteronism at diagnosis
《World Journal of Clinical Cases》2024年第18期3332-3339,共8页Debmalya Sanyal Pradip Mukhopadhyay Sujoy Ghosh 
BACKGROUND Primary hyperaldosteronism(PH)is considered to contribute to increased risk of developing type 2 diabetes mellitus(T2DM)and prediabetes.Both PH and DM are associated with increased risk for hypertension,car...
关键词：Primary hyperaldosteronism DIABETES PREDIABETES HYPERTENSION ALDOSTERONE Aldosterone to renin ratio 
Huoxue Jiedu Huayu recipe(活血解毒化瘀方)inhibits macrophage-secreted vascular endothelial growth factor-a on angiogenesis and alleviates renal fibrosis in the contralateral kidneys of unilateral ureteral obstruction rats
《Journal of Traditional Chinese Medicine》2024年第3期458-467,共10页GAO Xiaomeng QIANG Panpan CHANG Jingyue FAN Lili YANG Fan XU Qingyou 
Natural Science Foundation-funded Project:Effect of Macrophage-to-Myofibroblast Transition in Contralateral Kidney of Unilateral Ureteral Obstruction Rats Through the Aldosterone/MR/SGK1 Pathway and Inhibition of Chinese Herbs(No.81873251);Natural Science Foundation-funded Project:Aldosterone Stimulates MR Activation to Induce Lymphangiogenesis in the Contralateral Kidney of UUO Rats and the Protective Effect of Yiqi Jiedu Huayu Herbs(No.82174317);Hebei Provincial Postgraduate Innovative Ability Cultivation Funding Project:Aldosterone Induced Macrophages to Secrete VEGFA to Participate in Renal Angiogenesis and the Protective Effect of Huoxue Jiedu Huayu Recipe(CXZZBS2023140);Construction Program of New Research and Development Platform and Institution,Hebei Province Innovation Ability Promotion Plan under Grant No.20567624H。
OBJECTIVE:To elucidate the mechanism by which Huoxue Jiedu Huayu recipe(活血解毒化瘀方,HJHR)regulates angiogenesis in the contralateral kidney of unilateral ureteral obstruction(UUO)rats and the mechanism by which it ...
关键词：epithelial-mesenchymal transition ALDOSTERONE EPLERENONE receptors MINERALOCORTICOID unilateral ureteral obstruction Huoxue Jiedu Huayu recipe 
MicroRNA-155 mediates endogenous angiotensin II type 1 receptor regulation:implications for innovative type 2 diabetes mellitus management
《World Journal of Diabetes》2023年第9期1334-1340,共7页Konstantinos I Papadopoulos Alexandra Papadopoulou Tar-Choon Aw 
Type 2 diabetes mellitus(T2DM)is a lifelong condition and a threat to human health.Thorough understanding of its pathogenesis is acutely needed in order to devise innovative,preventative,and potentially curative pharm...
关键词：Angiotensin II Angiotensin II type 1 receptor Arginase 2 L-type calcium channel Mineralocorticoid receptor MiRNA-155 Renin-angiotensin aldosterone system Type 1/2 diabetes mellitus VERAPAMIL 
The Beneficial Effect of Renin-Angiotensin-Aldosterone System Blockade in Treatment of Hypertension, Resistant to Conventional Antihypertensives, in Patients on Maintenance Hemodialysis被引量：2
《Open Journal of Nephrology》2023年第2期67-73,共7页Kamel El-Reshaid Shaikha Al-Bader 
Background: Hypertension (HTN) is present in up to 90% of end stage kidney disease (ESRD) patients irrespective of the etiology of their kidney disease. Moreover, it is an important modifiable risk factor for progress...
关键词：ACEI ALDOSTERONE Angiotensin ARB HEMODIALYSIS HYPERTENSION RENIN Resistant Hypertension 
Huoxue Jiedu Huayu recipe(活血解毒化瘀方)alleviates contralateral renal fibrosis in unilateral ureteral obstruction rats by inhibiting the transformation of macrophages to myofibroblast被引量：2
《Journal of Traditional Chinese Medicine》2023年第1期105-112,共8页XIONG Yunzhao LIU Lingjin LIU Ziqian CHEN Gege HAO Juan GAO Xiaomeng QIANG Panpan WANG Zheng XU Qingyou 
Supported by Natural Science Foundation-funded Project:Effect of Macrophage-to-Myofibroblast Transition in Contralateral Kidney of Unilateral Ureteral Obstruction Rats Through the Aldosterone/MR/SGK1 Pathway and Inhibition of Chinese Herbs(No.81873251);Natural Science Foundation-funded Project:Aldosterone-induced Macrophage Polarization-lymphatic Endothelial Cell-like Transformation Involved in Renal Fibrosis and the Protective Effect of Yiqi Jiedu Huayu Herbs(No.82205006);Youth Top Talent Project of Hebei Provincial Department of Education:Mechanism of Renal Fibrosis Induced by NF-kB/IL-8 Induced MMT in UUO Rats(BJK2022004)。
OBJECTIVE:To investigate the action and underlying mechanisms of Huoxue Jiedu Huayu recipe(活血解毒化瘀方,HJHR)against unilateral ureteral obstruction(UUO)-induced injury in the contralateral kidney.METHODS:Forty-eigh...
关键词：ureteral obstruction renal fibrosis ALDOSTERONE receptors mineralocorticoid MACROPHAGES MYOFIBROBLAST Huoxue Jiedu Huayu recipe 
The effect of renin–angiotensin–aldosterone system inhibitors in patients with hypertension and COVID-19:A meta-analysis of randomized controlled trials and propensity score-matched studies
《Journal of Intensive Medicine》2022年第4期282-290,共9页Kai Zhang Lanxin Cao Nanxia Xuan Tiancha Huang Baoping Tian Wei Cui Gensheng Zhang Shufang Zhang 
supported in part by grants from the National Natural Science Foundation of China(Grant No.82100012,Kai Zhang);the Medical and Health Research Program of Zhe-jiang Province(Grant No.2022498722,Kai Zhang).
Background:High-quality evidence for whether the use of renin–angiotensin–aldosterone system(RAAS)in-hibitors worsens clinical outcomes for patients with coronavirus disease 2019(COVID-19)is lacking.The present stud...
关键词：COVID-19 HYPERTENSION RAAS Inhibitors ACEIs ARBS META-ANALYSIS 
Clinical characteristics and pre-surgery diagnostic criteria of aldosterone-producing adrenocortical carcinoma
《Chinese Medical Journal》2022年第20期2512-2514,共3页Xinyi Zhang Qingguo Lyu Jinfang Ma Xiaohui Pan Qiang Wei Jianwei Li Yuchun Zhu Sumin Shen Jing Li Yun ou Nanwei Tong 
1·3·5 project for disciplines of excellence, West China Hospital, Sichuan University(No. ZYGD18017)
To the Editor:Primary aldosteronism,characterized by hypertension,with or without hypokalemia,is the most frequent form of endocrine hypertension,which is mostly caused by bilateral adrenal hyperplasia or aldosterone-...
关键词：ALDOSTERONE HYPERTENSION SURGERY 
GRK5 is an essential co-repressor of the cardiac mineralocorticoid receptor and is selectively induced by finerenone
《World Journal of Cardiology》2022年第4期220-230,共11页Celina M Pollard Malka S Suster Natalie Cora Alexandra M Carbone Anastasios Lymperopoulos 
BACKGROUND In the heart,aldosterone(Aldo)binds the mineralocorticoid receptor(MR)to exert damaging,adverse remodeling-promoting effects.We recently showed that G protein-coupled receptor-kinase(GRK)-5 blocks the cardi...
关键词：ALDOSTERONE Cardiac myocyte Finerenone G protein-coupled receptor kinase-5 Mineralocorticoid receptor antagonist Signal transduction 
Diagnostic value of aldosterone to renin ratio calculated by plasma renin activity or plasma renin concentration in primary aldosteronism: a meta-analysis
《Chinese Medical Journal》2022年第6期639-647,共9页Zhenjie Liu Xiaohong Deng Li Luo Shaopeng Li Man Li Qinqin Deng Weiguo Zhong Qiang Luo 
supported by a grant from the Science and Technology Project of Guangdong Province(No.2016A020215136)。
Background:Since the diagnostic value of aldosterone to renin ratio(ARR)calculated by plasma renin concentration(PRC)or plasma renin activity(PRA)is still inconclusive,we conducted a meta-analysis by systematically re...
关键词：Primary aldosteronism Aldosterone to renin ratio Plasma renin activity Plasma renin concentration Diagnostic value META-ANALYSIS 
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