Introduction: Arterial hypertension is a common and serious medical condition, often contributing to significant cardiovascular morbidity and mortality. While the majority of hypertension cases are classified as prima...
BACKGROUND Primary hyperaldosteronism(PH)is considered to contribute to increased risk of developing type 2 diabetes mellitus(T2DM)and prediabetes.Both PH and DM are associated with increased risk for hypertension,car...
BACKGROUND The initial trials on angiotensin Ⅱ(AT Ⅱ)administration indicated a high incidence of thrombocytopenia and thrombosis,as well as a positive correlation between hyperreninemia and response to the medicatio...
Background: Hypertension (HTN) is present in up to 90% of end stage kidney disease (ESRD) patients irrespective of the etiology of their kidney disease. Moreover, it is an important modifiable risk factor for progress...
This study was supported by the Key R&D Program of Shandong Province(No.2020ZLYS05)。
BACKGROUND The efficiency of the target versus sub-target dose of renin–angiotensin system inhibitors(RASIs)in elderly patients with heart failure(HF)with reduced ejection fraction(HErEF)remains unclear.METHODS PubMe...
Over the past several decades,major strides have been made in the management of heart failure with reduced ejection fraction(HFrEF).The 2022 AHA/ACC/HFSA guidelines recommend four drug classes in all patients with sym...
supported in part by grants from the National Natural Science Foundation of China(Grant No.82100012,Kai Zhang);the Medical and Health Research Program of Zhe-jiang Province(Grant No.2022498722,Kai Zhang).
Background:High-quality evidence for whether the use of renin–angiotensin–aldosterone system(RAAS)in-hibitors worsens clinical outcomes for patients with coronavirus disease 2019(COVID-19)is lacking.The present stud...
OBJECTIVE:To examine whether specific stimulation of Shenshu(BL23)affects sympathetic nervous activity(SNA)-associated plasma renin concentration(PRC).METHODS:Eight healthy volunteers participated in three pattern con...