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The role of angiotensinⅡtype 1 receptor pathway in cerebral ischemia-reperfusion injury:Implications for the neuroprotective effectof ARBs: 《Neuroprotection》2024年第2期100-119,共20页Shuhan Huang Meng Zhang; Chongqing Science and Health Joint Medical ResearchProject,Grant/AwardNumber:2024MSXM124。; Cerebral ischemia-reperfusion(I/R)injury is a crucial factor that impacts the prognosis of recanalization therapy for acute ischemic stroke(AIS).It has been found that the brain renin-angiotensin system,especially the...; 关键词：acute ischemic stroke angiotensinⅡtype 1receptor blocker ischemia-reperfusion injury NEUROINFLAMMATION oxidative stress

制药废水中抗生素抗性的污染特征、检测手段和控制方法被引量：2: 《环境科学》2024年第2期844-853,共10页彭安萍高虎张新波; 国家自然科学基金项目(42107408)。; 制药行业废水中含有大量的抗生素、抗生素抗性细菌(ARBs)及抗性基因(ARGs)等新污染物,现今的生物处理工艺尚不能有效地对其进行去除.最终以上新污染物随出水进入各类水体或渗入土壤,造成环境污染,影响人类健康.因此,探明制药废水中抗生...; 关键词：制药废水抗生素抗性基因(ARGs) 抗性细菌(ARBs) 污染特征检测方法

Early initiation of ARBs without blood pressure risk via neutrophil membrane-fused pH-sensitive liposomes to reduce cardiomyocyte apoptosis after acute myocardial infarction被引量：1: 《Nano Research》2023年第7期9894-9905,共12页Jinfeng Gao Wusiman Yakufu Hongbo Yang Yanan Song Qiaozi Wang Qiyu Li Haipeng Tan Jing Chen Dili Sun Zhengmin Wang Jinyan Zhang Xueyi Weng Juying Qian Zhiqing Pang Qibing Wang Zheyong Huang Junbo Ge; The authors thank the Shiyanjia Lab(www.shiyanjia.com)for TEM measurements.The authors are grateful to Ms.Xiao Guo at the Joint Live Small Animal Imaging Laboratory of Fudan University Shanghai Medical College-PerkinElmer Company,for her technical support with the use of the in vivo imaging system.This work was financially supported by the National Key Research and Development Program of China(No.2016YFC1301200);the National Natural Science Foundation of China(Nos.82070281,81870269,and 82170524);Shanghai Clinical Research Center for Interventional Medicine(No.19MC1910300).; Activation of the local renin-angiotensin system(RAS)promotes cardiomyocyte apoptosis and cardiac remodeling after acute myocardial infarction(AMI).As an anti-RAS drug,the effect of Valsartan in the early stage of acu...; 关键词：VALSARTAN early initiation cardiomyocyte apoptosis blood pressure myocardial infarction

The effect of renin–angiotensin–aldosterone system inhibitors in patients with hypertension and COVID-19:A meta-analysis of randomized controlled trials and propensity score-matched studies: 《Journal of Intensive Medicine》2022年第4期282-290,共9页Kai Zhang Lanxin Cao Nanxia Xuan Tiancha Huang Baoping Tian Wei Cui Gensheng Zhang Shufang Zhang; supported in part by grants from the National Natural Science Foundation of China(Grant No.82100012,Kai Zhang);the Medical and Health Research Program of Zhe-jiang Province(Grant No.2022498722,Kai Zhang).; Background:High-quality evidence for whether the use of renin–angiotensin–aldosterone system(RAAS)in-hibitors worsens clinical outcomes for patients with coronavirus disease 2019(COVID-19)is lacking.The present stud...; 关键词：COVID-19 HYPERTENSION RAAS Inhibitors ACEIs ARBS META-ANALYSIS

吡格列酮联合ARBs与单用ARBs治疗糖尿病肾病的临床疗效Meta分析被引量：2: 《医学研究杂志》2022年第12期38-43,185,共7页曹玲艳樊文星陈广梅周勇丽何佳敏; 国家自然科学基金资助项目(82160142);云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(杰出青年培育项目)(202201AY070001-044);云南省卫生健康委员会医学学科带头人培养项目(D-2018027)。; 目的系统评价糖尿病肾病(diabetic kidney disease,DKD)患者在血管紧张素受体拮抗剂(angiotensin receptorblockers,ARBs)治疗基础上联用吡格列酮的临床疗效。方法检索CNKI、万方、EMBASE、PubMed、Cochrane Library等中外文数据库,纳...; 关键词：糖尿病肾病吡格列酮血管紧张素受体拮抗剂临床疗效 META分析

Selective targeted adsorption and inactivation of antibiotic-resistant bacteria by Cr-loaded mixed metal oxides: 《Frontiers of Environmental Science & Engineering》2022年第6期1-12,共12页Yanlin Li Bo Wang Lei Zhu Yixing Yuan Lujun Chen Jun Ma; support by the National Key Research and Development Program of China(No.2017YFA0207203);National Natural Science Foundation of China(Grant No.51978195).; Herein we provide a novel high-efficiency nanocomposite for bacterial capture based on mixed metal oxides(MMOs)with deleterious chromium properties.With both the layer structure of layered double hydroxides(LDHs)and t...; 关键词：Heavy metal adsorption Magnetic hydrotalcite ARBs removal Cr(VI)-MMOs combined antibacterial activity

中药联用ARBs治疗高血压病左心室肥厚疗效性与安全性系统评价被引量：1: 《亚太传统医药》2021年第5期136-141,共6页王越悦王凤荣王帅; 辽宁中医药临床重点学(专)科服务能力建设项目(LNZYXZK201908); 目的:分析中药联用血管紧张素受体拮抗剂(ARBs)治疗高血压病左心室肥厚(LVH)疗效与安全性。方法:计算机检索从建库至2019年12月31日PubMed、Cochrane Library、Embase、Web of Science、中国知网、维普、CBM、Wanfang Data数据库的文献...; 关键词：高血压病左室肥厚中医药 ARBS 系统评价

Ecological Analysis of the Influence of ACEIs and ARBs on the COVID-19 Prevalence and Death from COVID-19: 《Health》2021年第5期619-628,共10页Wan-Hui Liao Maciej Henneberg; Background: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-II receptor blockers (ARBs) have been an arguable risk factor for COVID-19 diseases because they could upregulate Angiotens...; 关键词：COVID-19 RAAS Inhibitors Ecological Analysis ACEIs ARBS

Prevalence of Chronic Kidney Disease in Patients with Cardiovascular Disease: 《Open Journal of Nephrology》2020年第3期227-240,共14页Said S. Khamis Ahmed M. Zahran Nagwa N. Hegazy Heba E. Kasem Hayam K. El-Fiky; Background: Chronic kidney disease (CKD) is a worldwide public health alarming problem. Although both heart and kidneys are separated by a quite distance within the body and they perform varied functi...; 关键词：Uncontrolled Hypertension Congestive Heart Failure Chronic Kidney Disease DIURETICS ACEI or ARBS

β受体阻滞剂联合ARBs对重症心力衰竭的治疗被引量：1: 《深圳中西医结合杂志》2020年第15期14-15,共2页陈莉丽彭淋李莉; 目的:研究在老年重症心力衰竭患者的治疗中采用β受体阻滞剂联合血管紧张素受体拮抗剂(ARBs)的临床意义。方法:选择2017年9月至2018年2月期间重庆西南铝医院接诊的68例老年重症心力衰竭患者纳入研究,按照奇偶法将患者均分为对照组(常规...; 关键词：心力衰竭 Β受体阻滞剂血管紧张素受体拮抗剂老年人

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