Type 2 diabetes mellitus(T2DM)is a lifelong condition and a threat to human health.Thorough understanding of its pathogenesis is acutely needed in order to devise innovative,preventative,and potentially curative pharm...
Type 1A diabetes mellitus(DMT1 in the following text)is caused by the autoimmune destruction of the insulin-producing beta cells in the islets of Langerhans[1,2].This destruction is determined by genetic susceptibilit...
the National Institute of Health,R01-NS097800 (to TI)。
Admission hyperglycemia is an independent predictor,that contributes to hemorrhagic transformation (HT),and worsened functional outcome following reperfusion therapy with tissue plasminogen activator (tPA) in ischemic...
supported by the National Institute of Health,No.R01-NS097800(to TI).
Dementia is currently the only leading cause of death that is still on the rise,with its overall costs already surpassing those of cancer and heart disease combined,it has developed into a worldwide crisis.In response...
The ACE2 receptor plays a central role in severe acute respiratory syndrome coronavirus 2 host cell entry and propagation.It has therefore been postulated that angiotensin converting enzyme inhibitors and angiotensin ...
Supported by National Natural Science Foundation of China(Study on the association between the composition of pungent traditional Chinese medicine and the effect of promoting blood circulation,No.81273901)
OBJECTIVE: To investigate the effect of osthole on isolated thoracic aortic rings, and to determine the potential mechanism of action.METHODS: Thoracic aortas were isolated from Wistar rats, and were suspended in tiss...
Salvia officinalis has been commonly used in Syria and other Middle East countries in popular medicine for many medical purposes. One of the strong claims about its properties is the spasmolytic effect. The aim of thi...
This study was supported by grants from the National Natural Science Foundation of China (No. 81072478 and No. 81273298) and Shanghai Municipal Commission of Health and Family Planning, Key Developing Disciplines (No. 2015ZB0501 ).
To the Editor: Osteoarthritis (OA) has the highest prevalence and economic impact among arthritic maladies and is the most common cause of long-term disability among individuals over 65 years of age. OA is characte...
Chronic rhinosinusitis (CRS) is a heterogeneous definition that includes different disease states that usually are associated with abnormal inflammatory responses. Besides being prevalent, the mechanisms involved in i...
The first case of Prinzmetal angina was described in 1959 by Prinzmetal, et al. Since this description, several triggering factors have been associated with vasospastic angina (VA) and included: illicit drugs such ...