Objective: to study and analyze the effect of dopamine combined with phentolamine in patients with pneumonia and heart failure and its effect on cardiac function. Methods: a total of 60 patients with pneumonia and hea...
supported by the CAMS Innovation Fund for Medical Sciences(2017-I2M-1-010,China);the Drug Innovation Major Project(2018ZX09711001-003-005,China);the Peking Union Medical College Graduate Innovation Fund Project(2017-1007-11).
Excessive nitric oxide(NO)causes extensive damage to the nervous system,and the adrenergic system is disordered in many neuropsychiatric diseases.However,the role of the adrenergic system in protection of the nervous ...
Supported by National Natural Science Foundation of China(Study on the association between the composition of pungent traditional Chinese medicine and the effect of promoting blood circulation,No.81273901)
OBJECTIVE: To investigate the effect of osthole on isolated thoracic aortic rings, and to determine the potential mechanism of action.METHODS: Thoracic aortas were isolated from Wistar rats, and were suspended in tiss...
Objective: To study the curative effect of silybin combined with pituitrin-phentolamine for pulmonary tuberculosis complicated by acute hemoptysis. Methods: A total of 78 patients with pulmonary tuberculosis complicat...
supported by the National Natural Science Foundation of China(Grant Nos.81373406 and 81421063)
Mitochondria are morphologically dynamic organelles which undergo fission and fusion processes. Our previous study found that arterial constriction was always accompanied by increased mitochondrial fission in smooth m...
supported by Jiangsu Province Natural Science Foundationof China:v2716298
Objective:To study the effects of phentolamine on myocardial extracellular matrix of cardiac remodeling induced by norepinephrine in rats.Methods:24 SD rats were divided into 3 groups randomly:control groups,norepinep...
AIM: To explore effects of exogenous and endogenous catecholamines on function of lymphocytes and primary mechanisms mediating the effects. METHODS: Splenocytes of rats were exposed to norepinephrine (NE), a- or p-adr...
Aim: To study the effect of intracavemous sodium nitropmsside (SNP), a nitric oxide (NO) donor, on penile erec-tion. Methods: Forty-two patients with erectile dysfunction (ED) were randomly assigned to receive SNP 300...
The effects of phentolamine on hemorrheology and hemodynamics were studied in dogs with acute liver damage induced by acetaminophen. After 1 h of phentolamine application , the viscosity of plasma and whole blood was ...