funded by the National Natural Science Foundation of China(Project No.32172453).
To explore non-food bioactive products for pesticide candidates,and high value-added application of crop plants in agriculture,by using osthole(a natural coumarin isolated from a Chinese herbal medicine Cnidium monnie...
Supported by the Talent Training Program for the Reform and Development of Local Colleges and University of the Central Government(2020GSP16);Postgraduate Innovative Research Project of Heilongjiang Bayi Agricultural University(YJSCX2022-Y59)。
Osthole has various pharmacological effects such as anti-cancer,anti-inflammation,prevention and treatment of cardiovascular diseases and neuroprotection.This paper reviews the advances in the research of the pharmaco...
funded by Laboratory of Lingnan Modern Agriculture Project(Award number NT2021006);supported by the National Natural Science Foundation of China(Award number 32102724);Pinduoduo-China Agricultural University Research Fund(No.PC2023A01002).
This study aimed to investigate the protective effect of the nature product osthole(OST)against Clostridium perfrin-gens type A infection-caused myonecrosis in a mouse model.Male mice were divided into(1)control,(2)in...
This work was supported by the National Natural Science Foundation of China(Nos.81573973 and 81774308);the Natural Science Foundation of Shanghai(No.20ZR1458600);the Outstanding Traditional Chinese Medicine Academic Leader Program of Shanghai(No.ZY(2018-2020)-RCPY-1011).
Metastasis is the leading cause of death in breast cancer patients.Osthole,as an active compound detected in the traditional Chinese medicine Wenshen Zhuanggu Formula,has shown a promising anti-metastatic activity in ...
Cancer is a serious threat to human life and a big problem in clinical treatment.Some natural active substances extracted from Traditional Chinese Medicine can effectively inhibit the growth of cancer cells,which is a...
Cancer is a serious threat to human life and a big problem in clinical treatment.Some natural active substances extracted from Traditional Chinese Medicine can effectively inhibit the growth of cancer cells,which is a...
the National Natural Science Foundation of China Grants (No. 81302764);the Science and Technology Grant for Excellent Talents of Harbin (No.2017RAXXJ060)。
Osthole is observed to have the capacity to treat pulmonary arterial hypertension(PAH) in rats, but molecular mechanism is still unknown. The present study aims to discover therapeutic targets and explore therapeutic ...
Supported by National Natural Science Foundation of China(Study on the association between the composition of pungent traditional Chinese medicine and the effect of promoting blood circulation,No.81273901)
OBJECTIVE: To investigate the effect of osthole on isolated thoracic aortic rings, and to determine the potential mechanism of action.METHODS: Thoracic aortas were isolated from Wistar rats, and were suspended in tiss...
National Natural Science Foundation of China(81703901);Shandong Province Natural Science Foundation of China(ZR2016HB56)
OBJECTIVE To investigate the effects of osthole on learning and memory impairment of AD mice induced by injection of Aβ25-35 and the content of Ca2+, GLU and Aβ1-42 in the brain tissue and peripheral blood. METHODS ...