CARVEDILOL

作品数：62被引量：137H指数：7
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相关领域：医药卫生更多>>
相关作者：潘卫三王士生陈新义王军奎姚晓伟更多>>
相关机构：同济大学沈阳药科大学西安交通大学陕西省人民医院更多>>
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相关基金：国家自然科学基金湖北省自然科学基金北京市自然科学基金国家教育部博士点基金更多>>
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M2-type macrophage membrane-mediated delivery of Carvedilol nanocomplex for acute liver failure treatment and remodeling inflammatory microenvironment
《Nano Research》2024年第7期6362-6375,共14页Mingge Shang Yaohui Zhang Junjie Qian Wenchao Wang Xizhi Yu Jiacheng Huang Lin Zhou Shusen Zheng 
supported by grants from the Research Unit Project of Chinese Academy of Medical Sciences(No.2019-I2M-5-030);the Research Project of Jinan Microecological Biomedicine Shandong Laboratory(No.JNL-2022002A);the Zhejiang Provincial Natural Science Foundation of China(No.LQ22H030009).
Interactions of hepatic macrophages with local inflammatory microenvironment is the key factor promoting the development of acute liver failure(ALF).Hence,reprogramming pro-inflammatory M1 into anti-inflammatory M2 ph...
关键词：acute liver failure hepatic drug delivery M2 macrophage-camouflaged nanoplatform inflammatory microenvironment macrophage polarization 
Carvedilol Versus Other Nonselective Beta Blockers for Variceal Bleeding Prophylaxis and Death: A Network Meta-analysis
《Journal of Clinical and Translational Hepatology》2023年第5期1143-1149,共7页Ka-Shing Cheung Chiu-Hang Mok Lok-Ka Lam Xian-Hua Mao Lung-Yi Mak Wai-Kay Seto Man-Fung Yuen 
Background and Aims:We aimed to perform a network meta-analysis(NWM)to examine comparative effectiveness of non-selective beta blockers(NSBBs)on prophylaxis of gastroesophageal variceal bleeding(GVB)and mortality bene...
关键词：NSBB CARVEDILOL NADOLOL PROPRANOLOL VARICES CIRRHOSIS CPSH 
Primary prophylaxis of variceal bleeding in patients with cirrhosis:A comparison of different strategies被引量：12
《World Journal of Gastrointestinal Endoscopy》2021年第12期628-637,共10页Ângelo Zambam de Mattos Carlos Terra Alberto Queiroz Farias Paulo Lisboa Bittencourt Alliance of Brazilian Centers for Cirrhosis Care–the ABC Group 
Patients with cirrhosis and esophageal varices bleed at a yearly rate of 5%-15%,and,when variceal hemorrhage develops,mortality reaches 20%.Patients are deemed at high risk of bleeding when they present with medium or...
关键词：CIRRHOSIS Esophageal varices Primary prophylaxis Non-selective betablockers CARVEDILOL Endoscopic variceal ligation 
Myocardial Protection with Beta Blocker Treatment in Infants with Heart Failure Due to Congenital Heart Defects and Duchenne Muscular Dystrophy被引量：1
《Open Journal of Thoracic Surgery》2020年第4期81-88,共8页Buchhorn Reiner 
Our first intention to treat infants’ heart failure with beta blockers was to improve the clinical condition as shown in our prospective randomized trial. We only use non-selective beta blockers in these infants, car...
关键词：Heart Failure Congenital Heart Disease Duchenne Muscular Dystrophy Pro-pranolol CARVEDILOL Cardiac Troponin T Myocardial Injury 
Clinical value of detecting autoantibodies against β1-, β2-, and α1-adrenergic receptors in carvedilol treatment of patients with heart failure被引量：2
《Journal of Geriatric Cardiology》2020年第6期305-312,共8页Dong-Yan HOU Lin XU Zhi-Yong ZHANG Xiao-Rong XU Xin WANG Juan ZHANG Jia-Mei LIU Hua WANG Jin CHEN Lin ZHANG 
the Beijing Natural Science Foundation (No. 7174306)。
Objective To determine the possible association of anti-β1-adrenergic receptors(anti-β1-AR), anti-β2-AR and anti-α1-AR with carvedilol treatment in patients with heart failure(HF). Methods A total of 267 HF patien...
关键词：Adrenergic receptors AUTOANTIBODIES Cardiac function CARVEDILOL Heart failure 
Management of hypertension in COVID-19被引量：1
《World Journal of Cardiology》2020年第5期228-230,共3页Daniel Antwi-Amoabeng Bryce D Beutler Alastair E Moody Zahara Kanji Nageshwara Gullapalli Christopher J Rowan 
The ACE2 receptor plays a central role in severe acute respiratory syndrome coronavirus 2 host cell entry and propagation.It has therefore been postulated that angiotensin converting enzyme inhibitors and angiotensin ...
关键词：Angiotensin converting enzyme inhibitor Angiotensin receptor blocker CARVEDILOL Coronavirus disease-19 COVID-19 SARS-CoV-2 VERAPAMIL 
Temperature and eluent composition effects on enantiomer separation of carvedilol by high-performance liquid chromatography on immobilized amylose-based chiral stationary phases被引量：1
《Journal of Pharmaceutical Analysis》2019年第5期324-331,共8页Cristina Panella Rosella Ferretti Adriano Casulli Roberto Cirilli 
Carvedilol is a chiral drug with potent antihypertensive and antianginal activities. Although it is clinically used as a racemic mixture, its enantiomers show different pharmacokinetic and pharmacodynamic profiles. He...
关键词：Chiralpak^(■) IG-3 Enantioselective HPLC CARVEDILOL Column temperature Isoenantioselective temperature Semipreparative enantioseparation 
Carvedilol vs endoscopic variceal ligation for primary and secondary prevention of variceal bleeding: Systematic review and metaanalysis被引量：7
《World Journal of Hepatology》2019年第5期464-476,共13页Michael Dwinata David Dwi Putera Muhamad Fajri Adda’i Putra Nur Hidayat Irsan Hasan 
BACKGROUND Variceal hemorrhage is associated with high mortality and is the cause of death for 20–30%of patients with cirrhosis.Nonselectiveβblockers(NSBBs)or endoscopic variceal ligation(EVL)are recommended for pri...
关键词：CARVEDILOL Liver CIRRHOSIS Variceal HEMORRHAGE PORTAL HYPERTENSION PROPHYLAXIS 
Exploring the utility of the Chasing Principle:influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
《Acta Pharmaceutica Sinica B》2019年第1期194-201,共8页Scheyla Daniela Siqueira J?rgensen Thomas Rades Huiling Mu Kirsten Graeser Anette Müllertz 
F.Hoffmann-La Roche Ltd.,Basel(1073861001);Switzerland for the financial support;the CAPES Foundation,Ministry of Education of Brazil,Brasília(009416/2013-07)for the financial support of Ph.D student Scheyla Siqueira
This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol(CAR), cinnarizine(CIN) or R3040 on drug solubilization in a twocompartment in vitro lipolysis mo...
关键词：Self-nanoemulsiying DRUG delivery system(SNEDDS) Chasing PRINCIPLE Two-compartment in vitro LIPOLYSIS Rat gastrointestinal conditions DRUG SOLUBILIZATION 
Impact of an acute hemodynamic response-guided protocol for primary prophylaxis of variceal bleeding被引量：7
《World Journal of Clinical Cases》2018年第13期611-623,共13页José Ignacio Fortea ángela Puente Patricia Ruiz Iranzu Ezcurra Javier Vaquero Antonio Cuadrado María Teresa Arias-Loste Joaquín Cabezas Susana Llerena Paula Iruzubieta Carlos Rodríguez-Lope Patricia Huelin Fernando Casafont Emilio Fábrega Javier Crespo 
Supported by Instituto de Investigación Sanitaria Marqués de Valdecilla,No.NVAL17/07(to Fortea JI);Instituto Carlos III,No.PI15/01083(to Vaquero J)
AIM To evaluate the long-term outcome of an acute hemodynamic response-guided protocol in which acute responders to intravenous propranolol received traditional nonselective beta-blockers(NSBBs) and acute nonresponder...
关键词：GASTROINTESTINAL HEMORRHAGE PROPRANOLOL CARVEDILOL Liver CIRRHOSIS PORTAL hypertension 
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