H2A is a nucleosome core subunit involved in organizing DNA into a chromatin structure that is often inacces- sible to regulatory enzymes. Replacement of H2A by its variant H2A.Z renders chromatin accessible at enhanc...
Linker histones, e.g., H1, are best known for their ability to bind to nucleosomes and stabilize both nucleosome structure and condensed higher-order chromatin structures. However, over the years many investigators ha...
Protein kinase RAF is strategically located in the "Ras - MAP-kinase signal transduction pathway". a principle system which transmits signals from growth factor receptors to the nucleus, resulting in cell proliferatio...