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REPORTER: 作品数：210被引量：154H指数：6; 导出分析报告; 相关领域：医药卫生经济管理更多>>; 相关作者：马凯胡红霞沈波周丹孙艳更多>>; 相关机构：南京医科大学广东省生物工程药物重点实验室上海市第十人民医院国家工程研究中心更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金上海市自然科学基金更多>>

The Reasoning Revolution: 《Beijing Review》2025年第10期22-23,共2页Peng Jiawei Zhao Xin Wang Wen Cai Yimao Shen Yujing Xie Yun; A shockwave echoed across the artificial intelligence(Al)industry in January as Chinese Al startup DeepSeek launched DeepSeek-R1,an open-source Al model that could match the capabilities of leading American chatbots.A...; 关键词：DEEP REVOLUTION REPORTER

SERS-tag techology in food safety and detection:sensing from the"fingerprint"region to the"biological-silent"region被引量：1: 《Journal of Future Foods》2024年第4期309-323,共15页Chen Chen Ximo Wang Ruiqiang Wang Geoffrey LN.Waterhouse Zhixiang Xu; financially supported by the Innovation Ability Improvement Project of Small and Medium-Sized Technology-Based Enterprises of Shandong Province (No.2022TSGC2409);GINW acknowledges funding from the MacDiarmid Institute for Advanced Materials and Nanotechnology and the Dodd Walls Centre for Photonic and Quantum Technologies.; Surface enhanced Raman spectroscopy(SERS)offers many advantages for the fast and sensitive detection of specific compounds,metal ions or pathogens in foods,motivating to its increasing utilization in food safety.SERS-...; 关键词：Surface enhanced Raman spectroscopy SERS-tags Raman reporter molecule Fingerprint region Biological-silent region Food Safety

Efficient and robust reverse genetics system for bovine rotavirus generation and its application for antiviral screening: 《Virologica Sinica》2024年第6期917-928,共12页Song-Kang Qin Kuan-Hao Li Ben-Jin Liu Cun Cao De-Bin Yu Zhi-Gang Jiang Jun Wang Yu-Xin Han Fang Wang Ying-Lin Qi Chao Sun Li Yu Ji-Tao Chang Xin Yin; supported by the Heilongjiang Provincial Natural Science Foundation of China(grant no.LH2033C107);the National Key Research and Development Program of China(2023YFD1801302);the Central Public-interest Scientific Institution Basal Research Fund(grant no.1610302022010).; Unveiling the molecular mechanisms underlying rotavirus replication and pathogenesis has been hampered by the lack of a reverse genetics(RG)system in the past.Since 2017,multiple plasmid-based RG systems for simian,hu...; 关键词：Bovine rotavirus(BRV) Optimized reverse genetics system Reporter virus High-throughput screen Small chemical compound

Rapid test for Mycobacterium leprae infection:a practical tool for leprosy: 《Infectious Diseases of Poverty》2024年第6期50-61,共12页Louise Pierneef Anouk van Hooij Danielle de Jong Gaby Wassenaar Els Verhard Elisa Tjon Kon Fat Nadine Engel Marufa Khatun Santosh Soren Abu Sufan Chowdhury Colette van Hees Paul Corstjens Annemieke Geluk; This study was made possible thanks to a grant from the Q.M.Gastmann-Wichers foundation(AG).; Background Detection of infection with Mycobacterium leprae allows timely prophylactic treatment,thereby reducing transmission as well as the risk of permanent,leprosy-associated nerve damage.However,since there is no...; 关键词：Mycobacterium leprae Diagnosis Lateral fow LEPROSY IGM Quantitative UCP-based rapid test Target product profle Upconverting reporter particle

Rapid generation and characterization of recombinant HCoV-OC43-VR1558 infectious clones expressing reporter Renilla luciferase: 《Biosafety and Health》2024年第6期350-360,共11页Fei Ye Na Wang Qiongge Guan Mengwei Wang Jiewei Sun Desheng Zhai Baoying Huang Ying Zhao Wenjie Tan; supported by the National Key Research and Development Program of China(2022YFC2304100 and 2021YFA1201003).; Viral infectious clones(ICs)serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics.However,the molecular profiles and complex limitations of human coronaviruses(HCoV...; 关键词：Infectious clones Human coronaviruses(HCoV)-OC43 Transformation-associated recombination(TAR) Reporter Renilla luciferase(Rluc)

Laccase is a multitasking protein for synthetic gene circuits in the yeast Saccharomyces cerevisiae: 《Synthetic and Systems Biotechnology》2024年第4期638-646,共9页Lifang Yu Michael Dare Asemoloye Mario Andrea Marchisio; Laccase is a multicopper oxidase enzyme that oxidizes a variety of substrates,including polyphenols and polycyclic aromatic hydrocarbons(PAHs).It catalyzes the four-electron reduction of molecular oxygen that results ...; 关键词：LACCASE S.cerevisiae Pulse generator Hydrocarbon degradation REPORTER

Correction:The RUBY reporter for visual selection in soybean genome editing: 《aBIOTECH》2024年第4期519-519,共1页Li Chen Yupeng Cai Xiaoqian Liu Weiwei Yao Shuiqing Wu Wensheng Hou; Correction:aBIOTECH https://doi.org/10.1007/s42994-024-00148-6 The copyright holder for this article was incorrectly given as‘Agricultural Information Institute,Chinese Academy of Agricultural Sciences’but should ha...; 关键词：AGRICULTURAL SOYBEAN REPORTER

SANGUINE SENTIMENTS: 《Beijing Review》2024年第38期19-19,共1页; At the Eighth Conference of Chinese and African Entrepreneurs,held in Beijing on September 6 as part of the 2024 Summit of the Forum on China-Africa Cooperation(FOCAC),business leaders from China and Africa shared the...; 关键词：AFRICA REPORTER GUI

The RUBY reporter for visual selection in soybean genome editing: 《aBIOTECH》2024年第2期209-213,共5页Li Chen Yupeng Cai Xiaoqian Liu Weiwei Yao Shuiqing Wu Wensheng Hou; supported by grants from the National Key Research and Development Program of China(2023YFD1202900);Hainan Yazhou Bay Seed Laboratory(B23YQ1504,B23CQ154P).; Current systems to screen for transgenic soybeans(Glycine max)involve laborious molecular assays or the expression of fluorescent markers that are difficult to see in soybean plants.Therefore,a visual system for early...; 关键词：SOYBEAN RUBY Visual reporter Genome editing Biotechnology

An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo被引量：2: 《Virologica Sinica》2024年第3期447-458,共12页Yingjian Li Xue Tan Jikai Deng Xuemei Liu Qianyun Liu Zhen Zhang Xiaoya Huang Chao Shen Ke Xu Li Zhou Yu Chen; supported by grants from the National Key R&D Program of China(2021YFA1300801 and 2018YFA0900801);National Natural Science Foundation of China(82172243 and 82372223);Fundamental Research Funds for the Central Universities(2042021kf0220 and 2042022dx0003).; The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is still epidemic around the world.The manipulation of SARS-CoV-2 is restricted to biosafety level 3 laboratories(BSL-3).In this study,we developed a SARS...; 关键词：SARS-CoV-2 RDP Antiviral evaluation Mouse model BSL-2

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