supported by the National Natural Science Foundation of China (31501857 to G.Z.and 31530077 to Z.Y.);the National Basic Research Program of China (2014CB138602 to Z.Y.)
Anti-Mullerian hormone (amh) is one of the earliest functional genes expressed during testicular differentiation. It has been suggested that androgen signaling regulates critical genes for the differentiation and de...
Project supported by the National Natural Science Foundation of China;China Postdoctoral Science Foundation.
SRY is the Y chromosomal gene which determines testis formation in human and mammals. SRY belongs to a family of genes that are related by sequence homology within the DNA-binding motif HMG-box. The genes most similar...
Project supported by the National "863-High-Technology-Project".
Mammalian embryos developing into males or females depend on whether they carryY chromosomes or not. Because a gene existing on the Y chromosome can induceindifferent gonad (genital ridge) to differentiate into testic...
Project supported by Shanghai Municipal Committee of Science
The recent advances in sex determination of eutherian mammals (including humans) have disclosed a gene on the short arm of the Y chromosome which initiates male development, termed SRY(sex-determining region of the y)...