supported by grants from the National Natural Science Foundation of China(No.81901324,82001378,82071395);China Postdoctoral Science Foundation(No.2021M693246);joint project of Chongqing Health Commission and Science and Technology Bureau(Chongqing,China)(No.2023QNXM009);Science and Technology Research Program of Chongqing Education Commission of China(No.KJQN202200435);Chongqing Talents:Exceptional Young Talents Project(Chongqing,China)(No.CQYC202005014);Natural Science Foundation of Chongqing,China(No.cstc2021ycjh-bgzxm0035,CSTB2022NSCQ-LZX0038);Key Research and Development Projects of Jining City,Shandong,China(No.2021YXNS057).
Epilepsy,one of the most common neurological disorders,is characterized by spon-taneous recurrent seizures.Temporal lobe epilepsy(TLE)is one of the most common medically intractable seizure disorders.Traf2-and NcK-int...
Supported by the Scientific Fund of Jiangsu Province(No.BY2015039-10);the Aquatic Three Project of Jiangsu Province(No.Y2017-37);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(TAPP);the Jiangsu Funding Program for Excellent Postdoctoral Talent。
Heat stress(HS)has been shown to adversely affect fish livers and can lead to extensive apoptosis.To investigate the relationship between endoplasmic reticulum(ER)stress and HS-induced apoptosis in fish livers,we isol...
supported by the grants from the National Science and Technology Innovation 2030 Major Project of China(No.2021ZD0203900);the Ministry of Science and Technology of China(Nos.2021ZD0203900 and 2019YFA0802103);the Department of Science and Technology of Zhejiang Province(No.2021C03104);the Guangzhou Science Innovation and Development Program(No.201803010092);the Shenzhen-Hong Kong Institute of Brain Science(No.NYKFKT2019006).
The liver plays a pivotal role in the regulation of lipid and glucose metabolism.However,increased intake of nutrients,including glucose,fructose,and saturated fat,induces hepatic de novo lipogenesis and subclinical i...