Chronic pancreatitis is an inflammatory disease of the pancreas that causes significant challenges to both patients and providers.The combination of excruciating pain often requires narcotic pain medications and leads...
Liver transplantation(LT)was first performed over six decades ago and is currently the standard of care for patients with end-stage liver disease and life-threatening complications.There have been significant advances...
Since the inception of solid organ transplantation through the 50s and 60s of the 20th century,transplantation has evolved into a major driver not only in the field of surgery,but immunology,pharmacology,pathology,int...
At present,there are no absolute practice guidelines for liver transplants in colorectal liver metastases(CRLM),and treatment protocols for unresectable CRLM are institution-specific(1).One of the first prospective st...
A better understanding of colorectal liver metastasis(CRLM)onco-genomics and the improvement of systemic treatments,including targeted and immune therapies,have shifted the paradigm of CRLM prognosis over the past two...
Liver resection plays a central role in the curative-intent treatment of both primary and metastatic liver tumors.While small,peripheral tumors can often be extirpated with non-anatomic limited resections,larger,centr...
Living-donor liver transplantation(LDLT)has been established as an alternative to deceased donor liver transplantation as a treatment option for patients with end-stage liver disease.Especially in Japan,where the numb...
When deciding for the optimal treatment to adopt in patients suffering from hepatocellular carcinoma(HCC),the surgical approach is commonly considered as the most curative option(1,2).The scarcity of donors for liver ...
Liver transplantation and hepatic resection are effective surgical strategies for hepatocellular carcinoma(HCC).In the current issue of Annals of Surgery,Professor Pinna and colleagues applied a cure model to compare ...
The role of bridging locoregional therapy(LRT)for patients with hepatocellular carcinoma(HCC)within Milan criteria before liver transplantation(LT)has been controversial.Recently,Agopian et al.(1)retrospectively inves...