Dear Editor, Telomeres, the natural ends of linear eukaryotic chro- mosomes, are essential for cell viability and genome integrity [ 1 ]. In mammalian cells, telomere repeat factors 1 and 2 (TRF1 and TRF2) are the ...
The study of the proteins that bind to telomeric DNA in mammals has provided a deep understanding of the mechanisms involved in chromosome-end protection. However, very little is known on the binding of these proteins...