BACKGROUND High-dose steroid administration is a common initial therapeutic approach for Vogt–Koyanagi–Harada disease(VKH).Nonetheless,administering substantial doses of steroids to pregnant women necessitates metic...
Background: Vogt-Koyanagi-Harada (VKH) disease is a rare, multisystem autoimmune disorder characterized by bilateral granulomatous panuveitis, with or without extraocular manifestations. Although its exact etiology an...
We thank the families for participation in this study,and we thank Novogene Technology Co.,Ltd.,for the WES sequencing and analysis.This work was supported by the National Natural Science Foundation Project of China(82070951,82271078);the National Natural Science Foundation Key Program(81930023);The Innovative Research Group Project of Chongqing Education Commission(CXQT19015);the Innovation Supporting Plan of Overseas Study of Chongqing(cx2018010);the National Key Clinical Specialties Construction Program of China,the Chongqing Branch of the National Clinical Research Center for Ocular Diseases,the Chongqing Key Laboratory of Ophthalmology(CSTC,2008CA5003);the Program for Youth Innovation in Future Medicine,Chongqing Medical University(w0047).
Vogt–Koyanagi–Harada(VKH)disease is a leading cause of blindness in young and middle-aged people.However,the etiology of VKH disease remains unclear.Here,we performed the first trio-based whole-exome sequencing stud...
患者男性,28岁。因“左眼视力下降”来我院就诊。眼科查体:右眼视力0.02,矫正视力1.0(-6.00 DS/-1.75DC×175°),左眼视力0.01,矫正视力0.4 (-6.00 DS/-1.25 DC×170)。眼压:右眼11 mm Hg (1 mm Hg=0.133k Pa),左眼10 mm Hg。裂隙灯检查...