ADMET

作品数:54被引量:100H指数:6
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相关领域:医药卫生理学更多>>
相关作者:蒋华良程铮王志郑思李姣更多>>
相关机构:华东理工大学上海理工大学中国科学院中国食品药品检定研究院化学药品检定所更多>>
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相关基金:国家自然科学基金国家科技重大专项福建省自然科学基金河北省自然科学基金更多>>
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Identification and molecular mechanism of angiotensin-converting enzyme inhibitory peptides from Larimichthys crocea titin被引量:7
《Food Science and Human Wellness》2020年第3期257-263,共7页Yue Fan Zhipeng Yu Wenzhu Zhao Long Ding Fuping Zheng Jianrong Li Jingbo Liu 
supported by The National Natural Science Funds of China(No.31901635).
This study aimed to identify novel ACEI peptides from Larimichthys crocea titin using in silico approaches and to clarify the molecular interaction mechanism.The hydrolyzed peptides of titin were compared with known A...
关键词:ACE peptide IDENTIFICATION In silico approaches ADMET Molecular docking 
Biological evaluation and interaction mechanism of beta-site APP cleaving enzyme 1 inhibitory pentapeptide from egg albumin被引量:3
《Food Science and Human Wellness》2020年第2期162-167,共6页Zhipeng Yu Sijia Wu Wenzhu Zhao Long Ding David Shiuan Fuping Zheng Jianrong Li Jingbo Liu 
This work was supported by the National Natural Science Funds of China(No.31901635);the National Key Research and Development Program of China(2018YFD0400301).
Inhibition of beta-site APP cleaving enzyme1(BACE1)is one of the most promising therapeutic approaches for Alzheimer’s disease.To find natural products for the treatment of Alzheimer’s disease,absorption,distributio...
关键词:Alzheimer’s disease BACE1 ADMET prediction Molecular docking Molecular dynamics KLPGF 
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