Health Commission of Hubei Province Medical Leading Talent Project,and Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University,Grant/Award Numbers:ZNJC201922,ZNJC202007;Key Research&Development Project of Hubei Province,Grant/Award Number:2020BCA069;National Natural Science Foundation of China,Grant/Award Numbers:81803065,81972852;Research Projects of Biomedical Center of Hubei Cancer Hospital,Grant/Award Number:2022SWZX12。
Background:Immunotherapy has revolutionized the therapeutical regimen for nasopharyngeal carcinoma(NPC),yet its response rate remains insufficient.Programmed death-ligand 1(PD-L1)on small extracellular vesicles(sEVs)m...