ALIX

作品数：10被引量：43H指数：2
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相关领域：医药卫生经济管理更多>>
相关作者：朱志宇孟哲峰陈宇唐明吕建新更多>>
相关机构：复旦大学中国科学院大学空军军医大学（第四军医大学）中国疾病预防控制中心更多>>
相关期刊：《International Journal of Oral Science》《病毒学报》《Signal Transduction and Targeted Therapy》《有机化学》更多>>
相关基金：国家自然科学基金中国博士后科学基金更多>>
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Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment
《International Journal of Oral Science》2025年第1期66-81,共16页Wenxiu Yuan Jiaqi Liu Zhenzhen Zhang Chengxinyue Ye Xueman Zhou Yating Yi Yange Wu Yijun Li Qinlanhui Zhang Xin Xiong Hengyi Xiao Jin Liu Jun Wang 
supported by National Natural Science Foundation of China(Nos.82271019,82472149,82471024);Sichuan Science and Technology Program(No.24ZDYF0099);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD-03-202101)to J.W.
The ambiguity of etiology makes temporomandibular joint osteoarthritis(TMJOA)“difficult-to-treat”.Emerging evidence underscores the therapeutic promise of exosomes in osteoarthritis management.Nonetheless,challenges...
关键词：OSTEOARTHRITIS ELEVATED LOADING 
Targeting the LMP1-ALIX axis in EBV^(+)nasopharyngeal carcinoma inhibits immunosuppressive small extracellular vesicle secretion and boosts anti-tumor immunity
《Cancer Communications》2024年第12期1391-1413,共23页Fajian He Yan Gong Gan Tao Jianguo Zhang Qiuji Wu Yushuang Tan Yajie Cheng Chunsheng Wang Jinru Yang Linzhi Han Zhihao Wang Yanping Gao Jingyi He Rui Bai Peikai Sun Xiaoyan Yu Yajuan Zhou Conghua Xie 
Health Commission of Hubei Province Medical Leading Talent Project,and Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University,Grant/Award Numbers:ZNJC201922,ZNJC202007;Key Research&Development Project of Hubei Province,Grant/Award Number:2020BCA069;National Natural Science Foundation of China,Grant/Award Numbers:81803065,81972852;Research Projects of Biomedical Center of Hubei Cancer Hospital,Grant/Award Number:2022SWZX12。
Background:Immunotherapy has revolutionized the therapeutical regimen for nasopharyngeal carcinoma(NPC),yet its response rate remains insufficient.Programmed death-ligand 1(PD-L1)on small extracellular vesicles(sEVs)m...
关键词：Epstein-Barr virus latent membrane protein 1 small extracellular vesicle PD-L1 ALIX nasopharyngeal carcinoma 
SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer被引量：2
《Signal Transduction and Targeted Therapy》2023年第12期5887-5903,共17页Xiayao Diao Chao Guo Hanhao Zheng Ke Zhao Yuming Luo Mingjie An Yan Lin Jiancheng Chen Yuanlong Li Yuting Li Xuehan Gao Jiaqi Zhang Mengxin Zhou Wenliang Bai Lei Liu Guige Wang Lanjun Zhang Xiaotian He Rusi Zhang Zhihua Li Changhao Chen Shanqing Li 
funded by the National High Level Hospital Clinical Research Funding(Grant No.2022-PUMCH-B-011);the National Key Research and Development Program of China(Grant No.2022YFA1305500);the National Natural Science Foundation of China(Grant No.32322023,82173272,81825016,82173230,82341018,82203662,82173271,82103416,82103536,82173266,82202276,and 81972385);the Key Areas Research and Development Program of Guangdong(Grant No.2022B1515120086,2021B1515020091,2022A1515140175,2021A1515010215,2023A1515011648,2022A1515012288,2021A1515010355);the Science and Technology Program of Guangzhou,China(Grant No.2023A04J2206).
Lymph node(LN)metastasis is one of the predominant metastatic routes of non-small cell lung cancer(NSCLC)and is considered as a leading cause for the unsatisfactory prognosis of patients.Although lymphangiogenesis is ...
关键词：METASTASIS inhibited LYMPHATIC 
血清外泌体中NY-ESO-1,Alix,PLAP联合对非小细胞肺癌的诊断价值被引量：10
《中南医学科学杂志》2020年第6期633-636,共4页王娟 潘鑫 徐永茂 
探讨血清外泌体中纽约食管鳞状细胞癌抗原-1(NY-ESO-1)、Alix、胎盘碱性磷酸酶(PLAP)联合对非小细胞肺癌的诊断价值。将早期非小细胞肺癌患者设为肺癌组、肺部良性疾病患者设为良性组、体检健康者设为对照组。结果显示,血清外泌体中NY-E...
关键词：血清 外泌体 纽约食管鳞状细胞癌-1 ALIX 胎盘碱性磷酸酶 非小细胞肺癌 诊断 
口腔鳞状细胞癌中ALG-2、Alix的表达及其意义被引量：1
《临床与实验病理学杂志》2015年第12期1361-1364,共4页朱志宇 陈宇 唐明 
目的探讨凋亡相关基因-2(apoptosis-linked gene-2,ALG-2)、Alix在口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)组织中的表达及其与临床病理特征的关系。方法收集原发性OSCC组织109例及正常口腔黏膜组织22例。采用免疫组化SP法检...
关键词：口腔肿瘤 鳞状细胞癌 ALG-2蛋白 Alix蛋白 
Synthesis and structures of malonate derivative-calix [4] arene conjugates
《Chinese Chemical Letters》2015年第7期914-917,共4页Wen-Jing Hu Ming-Liang Ma Yahu A.Liu Jiu-Sheng Li Biao Jiang Ke Wen 
Financial support from the National Natural Science Foundation of China (No. 21371177) is acknowledged
A series of malonate derivatives-calix[4]arene conjugates were synthesized through Knoevenagel condensation reaction between formyl-tetrapropoxycalix[4]arene and malonate derivatives. The structures of the resulting m...
关键词：arene Malonate derivatives Knoevenagel condensation reaction 
Heparanase activates the syndecan-syntenin-ALIX exosome pathway被引量：29
《Cell Research》2015年第4期412-428,共17页Bart Roucourt Sofie Meeussen Jie Bao Pascale Zimmermann Guido David 
Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan sulfate proteoglycans control the biogenesis of exosomes through their interaction with ...
关键词：heparan sulfate SYNDECAN HEPARANASE SYNTENIN exosome biogenesis exosomal cargo 
Alix Partners:中国汽车行业至2016年每年增幅将高达15%
《汽车与配件》2011年第24期42-43,共2页陈杰 
全球知名咨询公司AlxPartners（艾睿铂）董事总经理及上海办公室负责人罗曼表示，“在今年年初的几个月，中国的汽车市场经历了一段时间的放缓，这是因为政府取消对汽车行业的刺激政策以及对新车购买采取了部分限制，接下来的两个月里...
关键词：汽车行业 中国 咨询公司 汽车市场 负责人 办公室 总经理 消费者 
HIV-1感染对细胞内宿主因子TSG101及与Alix表达的影响被引量：1
《病毒学报》2011年第2期129-134,共6页胡辉亮 孟哲峰 张晓燕 吕建新 
国家自然基金青年项目(30901257);中国博士后基金第三批特别资助项目(201003233);国家十一五新药(2009ZX09303-006);国家十一五传染病研究重大专项(2008ZX10001-015)资助
探讨HIV-1感染宿主细胞后对其宿主蛋白肿瘤易感基因101蛋白(Tumor Susceptibility Gene 101,TSG101)及ALG-2相互作用蛋白X(ALG-2-interacting protein X,Alix)表达的影响。以HIV-1感染性克隆病毒pNL4-3感染TZM-bl PM1、Jurkat细胞株和...
关键词：HIV-1 感染 TSG101 ALIX 
Synthesis and Cation Complexation of Lariat Calix[4 ] crowns
《有机化学》2003年第z1期161-161,共1页SHI Zheng-Wei JIN Chuan-Ming LU Guo-Yuan 
Project supported by the National Natural Science Foundation of China.
　　Calixcrowns carrying bridging polyethyleneoxy moieties on the lower rim, which combine calixarene and crown ether in a single molecule, are a novel class of host compounds which have attracted increasing attention...
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