Barrett's esophagus(BE), a premalignant condition to Barrett's adenocarcinoma(BAC), is closely associated with chronic inflammation due to gastro-esophageal reflux. Caudal type homeobox 2(CDX2), a representative marke...
Barrett's esophagus is the strongest risk for esophageal adenocarcinoma(EAC). Metaplasia in patients with BE may progress to dysplasia and then invasive carcinoma. Well-defined diagnostic, progressive, predictive, and...
Supported by Barrett’s Oesophagus Campaign;the Wexham Gastrointestinal Trust,the Childwick Trust;the R.L.St J.Harmsworth Memorial Research Fund;the David and Frederick Barclay Foundation
Guidelines have been published regarding the management of Barrett's oesophagus(columnar-lined oesophagus). These have examined the role of surveillance in an effort to detect dysplasia and early cancer. The guideline...
The optimal management for low-grade dysplasia(LGD)in Barrett’s esophagus is unclear.In this article the importance of LGD is discussed,including the significant risk of progression to esophageal adenocarcinoma.Endos...