supported by the National Natural Science Foundation of China(Nos.82030107 and 81973247);Science and Technology Commission of Shanghai Municipality(Nos.19XD1400300,19430741400,19410761200)。
Nanocrystals are of great value in delivering poorly soluble drugs as a technique enables enhanced dissolution and bioavailability.The bottom-up technique allows better control of particle properties.However,the commo...
The authors acknowledge the support from the MOST 973 Program of China (No. 2006CB705600),from National Natural Science Foundation of China (No.10523001) ;the Research Fund for the Doctoral Program of Higher Education.
Water-soluble property is the precondition of biomedical evaluation and application of carbon nanotube (CNT). Novel water- soluble CNT was synthesized in this letter by grafting phosphoryl choline (PC) onto multi-...
Novel water-soluble prodrugs of combretastatin A-4 (5-8) were synthesized and evaluated for their in vitro cytotoxicity against lung carcinoma A549. Compound 5, bearing phosphoryl choline (PC) moiety, showed 90% i...