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作品数:66被引量:114H指数:5
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相关领域:医药卫生更多>>
相关作者:陈双扣胡道道廖智杨丽君梁华民更多>>
相关机构:吉林大学天津工业大学重庆医科大学华东理工大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划重庆大学研究生科技创新基金陕西省自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Targeting BPOZ-2 in Lewy body disease
《Neural Regeneration Research》2016年第6期910-911,共2页Avik Roy 
funded by MJ FOX Foundation Rapid Response Innovation Award Grant to AR
Formation of Lewy body inclusions(LBs)in the substantia nigra(SN)is a very well-characterized pathological hallmark of Parkinson’s disease(PD).LBs are aggregates of many biologically inactive proteins including...
关键词:Targeting substantia proteasome nigra ubiquitin biologically inactive mitochondria dopamine parkin 
Insights into the structural biology of G-protein coupled receptors impacts drug design for central nervous system neurodegenerative processes
《Neural Regeneration Research》2013年第24期2290-2302,共13页Farfán-García Eunice Dalet Trujillo-Ferrara José Guadalupe Castillo-Hernández María del Carmen Guerra-Araiza Christian Humberto Soriano-Ursúa Marvin Antonio 
supported by SIP-IPN,CONACYT (CB-168116);FIS/IMSS (FIS/IMSS/PROT/G11-2/1013)
In the last few years, there have been important new insights into the structural biology of G-protein coupled receptors. It is now known that allosteric binding sites are involved in the affinity and selec- tivity of...
关键词:neural regeneration G-Protein coupled receptors structural biology drug design neurodegenera-tive disorders   oligomedzation biased signaling Parkinson's disease Alzheimer's disease dopa-mine receptors muscarinic receptors grants-supported paper NEUROREGENERATION 
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