This work was supported by the grants from the National Natural Science Foundation of China (Nos. 31461143012 and 31530016), the National Basic Research Program of China (Nos. 2013CB911002 and 2015CB910601) to X.X., and from Young Talent Development Plan in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality (No. CIT&TCD201404158) and Beijing Nova Program Interdisciplinary Cooperation Project to J.L.
Deoxyribonucleic acid double-strand breaks (DSBs) are cytotoxic lesions that must be repaired either through homologous recombination (HR) or non-homologous end-joining (NHEJ) pathways. DSB repair is critical fo...