Project supported by the National Natural Science Foundation of China(Grant Nos.12174228 and 12274271)。
Two types of bound states in continuum(BICs),symmetry-protected and Brillouin zone folding driven,are identified in hollow Si nanorod arrays.By modulating the direction and distance of the air holes from the center of...
supported by the Natural Science Foundation of Guangdong Province,China(Grant No.2017A030310085);the Science and Technology Planning Project of Guangdong Province,China(Grant No.2018A050506034).
The mechanical stability of tRNAs contributes to their biological activities.The mitochondrial tRNAArg from Romanomermis culicivorax is the shortest tRNA ever known.This tRNA lacks D-and T-arms,represents a stem-bulge...
the National Natural Science Foundation of China(Grant Nos.11874309 and 11474237);the 111 Project(Grant No.B16029)。
Src SH3 protein domain is a typical two-state protein which has been confirmed by research of denaturant-induced unfolding dynamics.Force spectroscopy experiments by optical tweezers and atomic force microscopy have m...
the National Natural Science Foundation of China(Grant Nos.11504043,61671107,31670727,and 61771093);the Science Foundation of Shandong Province of China(Grant No.ZR2016JL027);the Taishan Young Scholars Program of Shandong Province of China(Grant No.tsqn20161049);the Youth Science and Technology Innovation Plan of Universities in Shandong,China(Grant No.2019KJE007)。
The hybrid atomistic structure-based model has been validated to be effective in investigation of G-quadruplex folding.In this study,we performed large-scale conventional all-atom simulations to complement the folding...
Project supported by the National Natural Science Foundation of China(Grant Nos.11175068 and 11474117);the Self-determined Research Funds of CCNU from the Colleges Basic Research and Operation of MOE,China(Grant No.230-20205170054)
An understanding of protein folding/unfolding processes has important implications for all biological processes, in- eluding protein degradation, protein translocation, aging, and diseases. All-atom molecular dynamics...
Project supported by the National Basic Research Program of China(Grant No.2013CB932803);the National Natural Science Foundation of China(Grant No.11574310);the Joint NSFC-ISF Research Program;jointly funded by the National Natural Science Foundation of China;the Israel Science Foundation(Grant No.51561145002)
Coarse-grained(CG) simulations can more efficiently study large conformational changes of biological polymers but usually lose accuracies in the details. Lots of different hybrid models involving multiple different ...
supported by Grants from the National Research Foundation through the Mechanobiology Institute Singapore and the Ministry of Education of Singapore(Grant No.MOE2012-T3-1-001)[to Yan J];the National Basic Research Program of China(Grant No.2013CB932800);the Major Research Plan of the National Natural Science Foundation of China(Grant Nos.91027046 and 91027045);the Fundamental Research Funds for the Central Universities(Grant No.2013121005)
The DNA i-motif is a quadruplex structure formed in tandem cytosine-rich sequences in slightly acidic conditions. Besides being considered as a building block of DNA nano-devices, it may also play potential roles in r...
Project supported by the National Natural Science Foundation of China(Grant No.51107016);the National Basic Research Program of China(Grant No.2013CB035605);the Postdoctoral Science Research Developmental Foundation of Heilongjiang Province,China(Grant No.LHB-Q12086)
Complex dynamical phenomenon was studied in the single phase H-bridge inverter which was controlled by either a peak current or a valley current. The state functions and the discrete iterative map equations were estab...
Project supported by the National Natural Science Foundation of China (Grant Nos 90103031, 10474041, 90403120 and 10021001), and the Nonlinear Project (973) of the NSM.
The folding dynamics and structural characteristics of peptides RTKAWNRQLYPEW (P1) and RTKQLYPEW (P2) are investigated by using all-atomic simulation procedure CHARMM in this work. The results show that P1, a segm...