GENE_TRANSFECTION

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Efficient gene transfection of suspension cells by highly branched poly(β-amino ester)
《Chinese Chemical Letters》2023年第7期176-181,共6页Delu Che Chenfei Wang Zhili Li Kaixuan Wang Shuaiwei Sun Xinyue Zhang Yi Li Zhengju Chen Lei Guo Yajing Hou Dezhong Zhou Songmei Geng 
funded by National Natural Science Foundation of China (NSFC, No. 51903202);the Innovation Capability Support Program of Shaanxi (No. 2022TD-48);the Key R&D Program of Shaanxi Province (No. 2020GXLH-Y-016)。
Suspension cells play a crucial role in many biological processes. However, compared to adherent cells, it is particularly challenging to introduce exogenous genes into suspension cells to regulate their biological fu...
关键词：Non-viral vector Highly branched poly(β-amino ester) Gene transfection High transfection efficiency Suspension cells Mast cells 
Pillar[5]arene-modified peptide-guanidiniocarbonylpyrrol amphiphiles with gene transfection properties
《Chinese Chemical Letters》2023年第5期246-249,共4页Kaiya Wang Minzan Zuo Tao Zhang Huilan Yue Xiao-Yu Hu 
supported by the Natural Science Foundation of Jiangsu Province(Nos.BK20200432,BK20211179);National Natural Science Foundation of China(Nos.22271154,M-0411);the Fundamental Research Funds for the Central Universities(Nos.NG2022003,NS2021040)。
Pillar[5]arene-modified amphiphilic peptides with varying numbers of guanidiniocarbonylpyrrol(GCP)moieties have been successfully synthesized,which can self-assemble to multivalent cationic superstructures in aqueous ...
关键词：arene Guanidinocarbonylpyrrole Gene transfection Amphiphiles Structure-activity relationship 
Highly branched poly(β-amino ester)s with narrow molecular weight distribution: Fractionation and gene transfection activity
《Chinese Chemical Letters》2023年第3期383-387,共5页Chenfei Wang Litao Sun Qiuxia Li Zhili Li Chengyuan Xu Xinyue Zhang Jianjun Shi Hao Zhou Wenxin Wang Dezhong Zhou 
funded by the National Natural Science Foundation of China(NSFC,No.51903202);Hainan Provincial Natural Science Foundation of China(No.521RC1058);the Key R&D Program of Shaanxi Province(No.2020GXLH-Y-016);the Natural Science Foundation of Shaanxi Province(No.2020JM-055);the Fundamental Research Funds for the Central Universities(No.xtr042019020);the Young Talents Support Plan of Xi’an Jiaotong University(No.HG6J002)。
Highly branched poly(β-amino ester)s(HPAEs) have shown their great promise in gene delivery. However, their broad molecular weight distribution(MWD) poses an additional challenge to the mechanistic understanding of t...
关键词：Gene transfection Non-viral vector Highly branched poly(β-amino ester)s FRACTIONATION Transfection activity 
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