GLIPIZIDE

作品数：12被引量：15H指数：2
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相关领域：医药卫生更多>>
相关作者：潘卫三聂淑芳欧阳德方孟晋吕永利更多>>
相关机构：沈阳药科大学中国医科大学天津市天和医院湖南医科大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《中国糖尿病杂志》《Journal of Diabetes Mellitus》《Open Journal of Physical Chemistry》更多>>
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  • 期刊=Asian Journal of Pharmaceutical Sciencesx
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Multi-dimensional visualization for the morphology of lubricant stearic acid particles and their distribution in tablets被引量：3
《Asian Journal of Pharmaceutical Sciences》2020年第1期60-68,共9页Liu Zhang Shailendra Shakya Li Wu Jiangtao Wang Guanghui Jin Huimin Sun Xianzhen Yin Lixin Sun Jiwen Zhang 
The authors are grateful for the financial support from the National Science and Technology Major Project(2017ZX09101001-006);Thanks to the BL13W1 beamline of the SSRF for the precious beam time and help from the team.
The shapes of particles and their distribution in tablets, controlled by pretreatment and tableting process, determine the pharmaceutical performance of excipient like lubricant. This study aims to provide deeper insi...
关键词：Stearic ACID MORPHOLOGY Spatial DISTRIBUTION SR-μCT GLIPIZIDE TABLETS 
Investigation of molecular aggregation mechanism of glipizide/cyclodextrin complexation by combined experimental and molecular modeling approaches被引量：2
《Asian Journal of Pharmaceutical Sciences》2019年第6期609-620,共12页Tianhe Huang Qianqian Zhao Yan Su Defang Ouyang 
supported by the University of Macao Research Grants(MYRG2016-00038-ICMS-QRCM and MYRG2016-00040-ICMS-QRCM);in part at the High-Performance Computing Cluster(HPCC)which is supported by Information and Communication Technology Office(ICTO)of the University of Macao
Cyclodextrin complexation is a wise strategy to enhance aqueous solubility of waterinsoluble drugs.However,the aggregation mechanism of drug-cyclodextrin complexes is still unclear.This research aimed to investigate t...
关键词：GLIPIZIDE CYCLODEXTRIN MOLECULAR modeling AGGREGATION MOLECULAR MECHANISM 
Effect of raw material variability of glipizide on the in vitro dissolution rate and in vivo bioavailability performance: The importance of particle size
《Asian Journal of Pharmaceutical Sciences》2019年第2期165-173,共9页Chenyao Zhao Chan Jin Hailing Gao Liyuan Wang Hongzhuo Liu Zhonggui He 
supported by National Science and Technology Major Projects for "Major New Drugs Innovation and Development"(No.2017ZX09101-001-005,Beijing,China)
The objective of this study was to understand the impact of active pharmaceutical ingredients(API) particle size on a re-developed generic product of glipizide and to improve its formulation so that it exhibits bioequ...
关键词：GLIPIZIDE Particle size Product quality BIOEQUIVALENCE study DISSOLUTION 
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