the National Key Research and Development Program of China(2017YFC1600403);the National Natural Science Foundation of China(31830068,21822806);the Fundamental Research Funds for the Central Universities(JUSRP51701A);the National First-class Discipline Program of Light Industry Technology and Engineering(LITE2018-08);the Distinguished Professor Project of Jiangsu Province.
2-keto-D-gluconic acid(2-KGA)is a key precursor for synthesising vitamin C and isovitamin C.However,phage contamination is as constant problem in industrial production of 2-KGA using Pseudomonas fluorescens.Gluconobac...