This work was supported by The National Key Basic Research Program(973 Program)of China(2012CB917104 and 2013CB967201);National Natural Science Foundation of China Program grant(No:81372445);National Institute of Health grant(AI109317-01A1 and AI109373-01).
Tumor escape from immune-mediated destruction has been associated with immunosuppressive mechanisms that inhibit T-cell activation.A promising strategy for cancer immunotherapy is to disrupt key pathways regulating im...
This work was supported by grants from National Basic Research Program of China (2012CB910800 to BS), the National Natural Science Foundation (81072029 to BS and 30901750, 81272322 to YC, 81201528 to RJ), Major Research Plan of the National Natural Science Foundation (91029721 to BS), Natural Science Foundation of Jiangsu Province (BK2010532 to YC), China Postdoctoral Science Foundation-funded project (20090461133 to YC), Jiangsu Planned Projects for Postdoctoral Research Funds (1001028B to YC), Jiangsu Province Laboratory of Pathogen Biology (11BYKF02 to QS), Ministry of Health Research Foundation, China (LW201001 to LD) and the Priority Academic Program Development of Jiangsu Higher Education Institutions. The work was also supported in part by the Program for Development of Innovative Research Teams in the First Affiliated Hospital of NJMU.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) secreting cellular tumor vaccines contribute to the induction of potent antitumor immune responses in murine models and patients suffering from cancers. Hepa...