supported in part by grants from the Ministry of Health of China (Nos. 2012ZX09304-011, 2013ZX09401003-005, 2013ZX09507001 and 2013ZX09507002);Shanghai Science and Technology Development Fund (No. 13DZ2290300);Thousand Talents Program in China
The structure–activity relationship(SAR) study of a 1 2 3 4 4a 9a-hexahydro-1H-xanthene series of selective,human glucocorticoid receptor a(hGRa) antagonists is reported.Compounds were screened using hydroxyapati...
5-Substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N'-dibenzyl-1, 2-ethylenediamine and methyl 2, 4-dibromide butyrate through nucleophilic substitution, reduction, chlorination, deben...
the Shanghai Development Fund of Science and Technology.
substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N?-dibenzyl-1,3-propylene diamine and methyl-2,3-dibromo propionate through nucleophilic substitution, reduction, chlorination and debe...
A new binuclear bisphthalocyanine-tetrahydroxo(hexa-tetradecanobisphthalocyani-nato) disilicum is synthesized and characterized. and one of its important applications isintroduced.
Aluminum chloride induced Diels-Alder reactions of 3-carboethoxy- and 3-carbonitrile-2-cyclohexen-1-one with cyclopentadiene, isoprene and (E)-piperylene were described. Thestereochemistry of the adducts were confirme...