云南高校图书馆联盟文献共享服务平台- HIGHLY

HIGHLY: 作品数：1188被引量：2431H指数：16; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：毛金成王子川周妮妮吴小婷周辉更多>>; 相关机构：苏州大学中国科学院上海交通大学大连理工大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Highly anticipated natural diterpenoids as an important source of new drugs in 2013-2023: 《Chinese Chemical Letters》2025年第1期119-136,共18页Yingjie Wang Peng Tang Wenchao Tu Qi Gao Cuizhu Wang Luying Tan Lixin Zhao Hongye Han Liefeng Ma Kouharu Otsuki Weilie Xiao Wenli Wang Jinping Liu Yong Li Zhajun Zhan Wei Li Xianli Zhou Ning Li; This review covers the structures of diterpenoids,including chain(72),monocyclic(9),labdane-type(67),clerodane-type(127)abietane-type(716),ent-kaurane-type(89),grayanane-type(331),ingenanetype(55),tigliane-type(154),d...; 关键词：Natural diterpenoids Structures BIOACTIVITIES Druggability Leading compounds New drugs

Highly robust supramolecular polymer networks crosslinked by metallacycles: 《Chinese Chemical Letters》2024年第12期7-9,共3页Xiaoman Dang Zhiying Wu Tangxin Xiao Zhouyu Wang Leyong Wang; Supramolecular polymer networks(SPNs), which integrate principles from both supramolecular chemistry and traditional polymer science, offer a multitude of advantages, including dynamic,reversible, recoverable, and sti...; 关键词：materials POLYMER BONDS

Neosophoflavonoids A–C, A class of highly oxidized hybrid flavonoids from Sophora flavescens with antidiabetic effects: 《Chinese Chemical Letters》2024年第10期295-298,共4页Xu Zhang Jiang Li Kai-Zhou Lu Ya-Nan Yang Jian-Shuang Jiang Xiang Yuan Zi-Ming Feng Fei Ye Pei-Cheng Zhang; supported by the National Natural Science Foundation of China(No.81973194);Biomedical High Performance Computing Platform,Chinese Academy of Medical Sciences。; Three highly oxidized hybrid flavonoids neosophoflavonoids A–C(1,2a,and 2b)were isolated from the roots of Sophora flavescens.Neosophoflavonoid A possesses a unique highly oxidized heptacyclic6/6/6/6/6/6/5 system.Neo...; 关键词：Sophora flavescens Highly oxidized hybrid flavonoids Neosophoflavonoids A-C PTP1B inhibition Lipid accumulation inhibition

(+)/(-)-Mycosphatide A,a pair of highly oxidized polyketides with lipid-lowering activity from the mangrove endophytic fungus Mycosphaerella sp.SYSU-DZG01: 《Chinese Chemical Letters》2024年第9期210-213,共4页Qi Tan Run-Zhu Fan Wencong Yang Ge Zou Tao Chen Jianying Wu Bo Wang Sheng Yin Zhigang She; National Natural Science Foundation of China(Nos.U20A2001,81973195,21877133);the Guangdong Marine Economy Development Special Project(Nos.GDNRC[2022]35,GDNRC[2023]39)。; (±)-Mycosphatide A(1a/1b),a pair of highly oxidized enantiomeric polyketides featuring a unique5/5/6/5-fused tetracyclic ring system,were isolated from the mangrove endophytic fungus Mycosphaerella sp.SYSU-DZG01.Thei...; 关键词：Mangrove endophytic fungus Mycosphaerella sp. Polyketide Highly oxidized Lipid-lowering activity

Highly reversible photomodulated hydrosoluble stiff-stilbene supramolecular luminophor induced by cucurbituril: 《Chinese Chemical Letters》2024年第8期235-239,共5页Guoxing Liu Yixin Li Changming Tian Yongmei Xiao Lijie Liu Zhanqi Cao Song Jiang Xin Zheng Caoyuan Niu Yun-Lai Ren Liangru Yang Xianfu Zheng Yong Chen; National Natural Science Foundation of China (No.21801063);Top-Notch Talents Program of Henan Agricultural University (No.30501049);Natural Science Foundation of Henan Province (No.232300420132);the Merit Funding for the Oversea Staff of Henan Province for financial support; A photochromic molecular rotor based on stiff-stilbene(SSB-FMR)was handily prepared through coupled reaction,and further self-assembled with cucurbit[8]uril(CB[8])to form a 2:2 quaternary supramolecu-lar complex(SSB-F...; 关键词：Host-guest complexation CUCURBITURIL Fluorescence switch Stiff-stilbene Fluorescence enhancement

Highly-chlorinated inert and robust interphase without mineralization of oxide enhancing high-rate Li metal batteries: 《Chinese Chemical Letters》2024年第6期239-243,共5页Long Li Kang Yang Chenpeng Xi Mengchao Li Borong Li Gui Xu Yuanbin Xiao Xiancai Cui Zhiliang Liu Lingyun Li Yan Yu Chengkai Yang; supported primarily by National Natural Science Foundation of China(Nos.22109025,51972061);National Key Research and Development Program of China(No.2020YFA0710303);Natural Science Foundation of Fujian Province,China(No.2021J05121)。; Side reactions and dendrite growth triggered by the unstable interface and inhomogeneous deposition have become the biggest obstacle to the commercialization for lithium metal batteries.In this study,a highly-chlorina...; 关键词：Highly-chlorinated Water/oxygen resistance Stable interphase Dendrite-free lithium metal batteries High-rate

Highly dispersed Ru nanospecies on N-doped carbon/MXene composite for highly efficient alkaline hydrogen evolution被引量：1: 《Chinese Chemical Letters》2024年第4期153-159,共7页Minying Wu Xueliang Fan Wenbiao Zhang Bin Chen Tong Ye Qian Zhang Yuanyuan Fang Yajun Wang Yi Tang; financially supported by the National Key R&D Program of China (No.2018YFA0209402);the National Natural Science Foundation of China (Nos.22088101, 22175132, 22072028)。; Hydrogen has emerged as a promising environmentally friendly energy source. The development of lowcost, highly active, stable, and easily synthesized catalysts for hydrogen evolution reactions(HER) remains a significa...; 关键词：HER activity Highly dispersed Ru-based catalysts MXene Alkaline condition

Highly elastic and degradable vitrimeric elastomers using polycondensation: 《Chinese Chemical Letters》2024年第3期434-438,共5页Yue Liu Yongshuang Huang Chao Li Guifu Si Min Chen; supported by National Natural Science Foundation of China(NSFC,Nos.21971230,U19B6001,22201003);Excellent Research and Innovation Team Project of Anhui Province(No.2022AH010001);Anhui Province Key Laboratory of Environment-friendly Polymer Materials。; Introducing covalently crosslinked network to polymer matrix can merge the advantages in reprocessing and durability of polymers.In this contribution,a series of high-performance vitrimeric elastomers were achieved vi...; 关键词：POLYCONDENSATION Vitrimeric elastomers Highly elastic Degradable polymers

Identification of highly efficacious PROTACs targeting BRD4 against acute myeloid leukemia:Design,synthesis,and biological evaluations: 《Chinese Chemical Letters》2023年第6期426-431,共6页Aiping Chen Yue Zhong Yunxiao Liu Zhancheng Xie Hanyu Wu Wei Shi Wenlong Huang Renxiang Tan Hai Qian; the National Science Foundation of China(Nos.81872733,82173674,and 81872734);the Research&Development Project in Key Areas of Guangdong Province(No.2019B020203003)for supporting this study。; The abnormal activation of BRD4 accelerates the progression of acute myeloid leukemia(AML),developing more precise therapeutics to intervene BRD4 promise to be an excellent opportunity to avoid current limitations of ...; 关键词：Acute myeloid leukemia BRD4 PROTACs Protein degradation APOPTOSIS

Highly emissive perylene diimide-based bowtie-shaped metallacycles: 《Chinese Chemical Letters》2023年第4期296-299,共4页Yali Hou Ruping Shi Hongye Yuan Mingming Zhang; supported by the National Natural Science Foundation of China (No. 22171219);the Fundamental Research Funds for the Central Universities (No. xzy022021004)。; Metallacycles hold great promise for fluorescence-based sensing due to their synthetic advantages and unique physicochemical properties. However, it remains highly challenging to develop a versatile methodology for co...; 关键词：Fluorescence materials Emissive metallacycles SELF-ASSEMBLY Perylene diimide Picric acid sensing

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