HOMOLOGOUS

作品数：202被引量：441H指数：8
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Discrepant involvement of homologous repair and non-homologous end joining pathways in maize development and growth
《The Crop Journal》2025年第2期406-417,共12页Shuanghui Zhao Leiming Zheng Minghui Zheng Menghan Li Shuyue Li Nan Wu Yan He Jinghan Liu 
supported by the National Natural Science Foundation of China(32372116)to Yan He.
Chromosomal DNA double-strand breaks(DSBs)are often generated in the genome of all living organisms.To combat DNA damage,organisms have evolved several DSB repair mechanisms,with nonhomologous end-joining(NHEJ)and hom...
关键词：Homologous recombination Non-homologous end joining Double-strand break MAIZE 
PAMPHLET:PAM Prediction HomoLogous-Enhancement Toolkit for precise PAM prediction in CRISPR-Cas systems
《Journal of Genetics and Genomics》2025年第2期258-268,共11页Chen Qi Xuechun Shen Baitao Li Chuan Liu Lei Huang Hongxia Lan Donglong Chen Yuan Jiang Dan Wang 
supported by grants from the Foundation for Distinguished Young Talents in Higher Education of Guangdong,China(2024KQNCX157);Our work was also supported in part by the Guangdong Provincial Key Laboratory of Interdisciplinary Research and Application for Data Science,BNU-HKBU United International College(2022B1212010006);in part by the Guangdong Higher Education Upgrading Plan(2021-2025)of“Rushing to the Top,Making Up Shortcomings and Strengthening Special Features”(R0400001-22);Additionally,we acknowledge support from the Zhuhai Basic and Applied Basic ResearchFoundation(2220004002717).
CRISPR-Cas technology has revolutionized our ability to understand and engineer organisms,evolving from a singular Cas9 model to a diverse CRISPR toolbox.A critical bottleneck in developing new Cas proteins is identif...
关键词：CRISPR-Cas Protospacer adjacentmotif Genome editing PAM prediction Computational framework 
Visible-light-responsive homologous heterostructure of oxynitrides constructed to boost charge separation and water splitting
《Science China Chemistry》2025年第1期186-191,共6页Hai Zou Yunfeng Bao Xueshang Xin Yu Qi Tengfeng Xie Fuxiang Zhang 
supported by the National Natural Science Foundation of China(22332005,21925206,22279138,22261160369,22302194,22409022);the Dalian Supports High-level Talent Innovation and Entrepreneurship Projects(2020RD06);the China Postdoctoral Science Foundation(2023M743423 and 2024T170899)。
Constructing typeⅡheterostructures represents a widely recognized strategy for enhancing charge separation and photocatalytic efficiency,but it remains challenging to fabricate homologous heterostructures based on vi...
关键词：charge separation HETEROSTRUCTURE OXYNITRIDE photocatalysis visible light 
A deterministic model for homologous antibody dependant enhancement on influenza infection
《Infectious Disease Modelling》2024年第4期1265-1275,共11页Shilian Xu Jiaru Yang 
Antibody dependant enhancement refers that viral infectivity was unexpectedly enhanced at low antibody concentration compared to when antibodies were absent,such as Dengue,Zika and influenza virus.To mathematically de...
关键词：Antibody dependent enhancement Logistical function Switching function Influenza virus 
Structural variations in oil crops:Types,and roles on domestication and breeding
《Oil Crop Science》2024年第4期240-246,共7页Xiaobo Cui Miao Yao Meili Xie Ming Hu Shengyi Liu Lijiang Liu Chaobo Tong 
funded by the National Natural Science Foundation of China(32370693 and U20A2034);Innovation Program of Chinese Academy of Agricultural Sciences(CAAS-CSIAF-202402);the Young Top-notch Talent Cultivation Program of Hubei Province for Dr.Chaobo Tong,the National Key Research and Development Program of China(2021YFD1600500);Central Public-interest Scientific Institution Basal Research Fund(2021-2060302-061-027,2021-2060302-061-029).
Structural variations(SVs),a newly discovered genetic variation,have gained increasing recognition for their importance,yet much about them remains unknown.With the completion of whole-genome sequencing projects in oi...
关键词：Structural variations Oil crops Copy number variations Presence or absence variations Homologous exchanges 
A dose-dependent bimodal switch by homologous Aux/IAA transcriptional repressors被引量：1
《Molecular Plant》2024年第9期1407-1422,共16页Hyung-Taeg Cho Minsu Lee Hee-Seung Choi Kwang-Ho Maeng Kyeonghoon Lee Ha-Yeon Lee Anindya Ganguly Hoonyoung Park Chang-Hoi Ho 
supported by a grant from the National Research Foundation(NRF-2022R1A2C1007862).
Combinatorial interactions between different regulators diversify and enrich the chance of transcriptional regulation in eukaryotic cells.However,a dose-dependent functional switch of homologous transcriptional repres...
关键词：AUXIN AUX/IAA dose-dependent regulation root hair transcription TOPLESS(TPL) 
Ethnopharmacology,chemical composition and functions of Cymbopogon citratus被引量：1
《Chinese Herbal Medicines》2024年第3期358-374,共17页Xiqin Du Meng Zhang Shuping Wang Jingyang Li Jingze Zhang Dailin Liu 
supported by the National Key R&D Program of China(No.2022YFC3501805)for financial support.
Cymbopogon citratus in the gramineous family,also known as lemongrass(LG),is a perennial herb.LG,a drug and food homologous medicine,has a widely recorded medicinal value and food applications.To date,158 LG compounds...
关键词：chemical composition Cymbopogon citratus(DC.)Stapf drug and food homologous medicine ETHNOPHARMACOLOGY LEMONGRASS medicine and food applications 
Characterization,Expression Pattern Analysis,and Cellular Localization of Two Homologous MUC2 Genes in Japanese Flounder(Paralichthys olivaceus)
《Journal of Ocean University of China》2024年第4期1035-1044,共10页ZHU Ying YANG Xinsheng LI Zhengjie LI Chao 
supported by the Natural Science Foundation of Shandong Province (No.ZR2022QC037);the Shandong Key R&D Program for Academician Team in Shandong (No.2023ZLYS02);the High-Level Talents Research Fund of Qingdao Agricultural University (No.663/1120033);the Young Experts of Taishan Scholars (No.201909130);the Shandong Technical System of Fish Industry (No.SDAIT-12-03);the Science and Technology Support Plan for Youth Innovation of Colleges and Universities in Shandong Province (No.2019KJF003)。
As a member of mucins family,MUC2 is an important component of mucus,which is characterized by tandem and irregular repeat sequences rich in threonine and serine.It is strongly expressed by goblet cells that are invol...
关键词：MUC2 ISH Edwardsiella tarda Paralichthys olivaceus 
Genome-wide CRISPR screening identifies critical role of phosphatase and tensin homologous (PTEN) in sensitivity of acute myeloid leukemia to chemotherapy
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第8期700-710,共11页Liming LIN Jingjing TAO Ying MENG Yichao GAN Xin HE Shu LI Jiawei ZHANG Feiqiong GAO Dijia XIN Luyao WANG Yili FAN Boxiao CHEN Zhimin LU Yang XU 
supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY21H080005);the National Natural Science Foundation of China(Nos.81572920 and 82100171).
Although significant progress has been made in the development of novel targeted drugs for the treatment of acute myeloid leukemia(AML)in recent years,chemotherapy still remains the mainstay of treatment and the overa...
关键词：Genome-wide clustered regularly interspaced short palindromic repeats(CRISPR)library Phosphatase and tensin homologous(PTEN) Rapamycin Acute myeloid leukemia(AML) CHEMOTHERAPY 
Homologous heterostructure of MoS_(2) and MoO_(2) coupled with carbon layers as cathode catalyst for rechargeable lithium-oxygen batteries
《Rare Metals》2024年第7期3383-3390,共8页Yi-Ming Zhang Zhao-Rui Zhou Lan-Ling Zhao Ye-Bing Li Rui-Feng Li Ya Zhou Sana Shoukat Abulgasim-Ahmed-Abbaker Adam Jun Wang 
financially supported by Guangdong Basic and Applied Basic Research Foundation (No. 2021A1515111124);National Key Research and Development Program of China (Nos.2022YFB3505104 and 2022YFB3706604);Natural Science Foundation of Shandong Province (Nos. ZR2022JQ19,ZR2020YQ32 and ZR2020QB122);the National Natural Science Foundation of China (Nos.51971119 and 52171141);Young Scholars Program of Shandong University (No. 2019WLJH21)。
Lithium-oxygen batteries tend to experience high overpotentials because of the sluggish oxygen reduction reaction and oxygen evolution reaction during cycling.A potential solution to address this issue is to develop a...
关键词：LITHIUM process. kinetics 
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