supported by the National Natural Science Foundation of China(No.82271889,82371173);the National Key Research and Development Program of China(No.2021YFC2701000);the Natural Science Foundation Project of Shanghai Science and Technology Innovation Action Plan(China)(No.23ZR1409400);Shanghai Science and Technology Commission of China(No.21DZ2200700).
Microtia,a congenital malformation affecting the external and middle ear,arises from disruptions during the development of embryonic branchial arches and cranial neural crest cells(CNCCs),making it the second most pre...