Human adaptive immunity involves the production and secretion of antibodies by differentiated B cells(ie.,antibody-secreting cells,also called plasma cells)in response to antigens.These secreted antigen-specific antib...
In the sentence beginning"H chain genes are assembled from one functional variable(B),one diversity(D),and.."in this article,the text should have read"H chain genes are assembled from one functional variable(M),one di...
support from the Netherlands Organization for Scientific Research(NOW)funding the Netherlands Proteomics Centre through the X-omics Road Map program(project 184.034.019)and Gravitation Subgrant 00022 from the Institute for Chemical Immunology.AJRH acknowledges support from the Netherlands Organization for Scientific Research(NOW)through the Spinoza Award SPI.2017.028 to AJRH.The COVID MILK studies was funded by Stichting Steun Emma Kinderziekenhuis.KAD acknowledges the Amsterdam Reproduction and Development Institute for funding this work though the AR&D grant(V.000296).
The most abundant immunoglobulin present in the human body is IgA. It has the highest concentrations at the mucosal lining and in biofluids such as milk and is the second most abundant class of antibodies in serum. We...