MITOTIC

作品数:63被引量:108H指数:6
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相关领域:生物学医药卫生更多>>
相关作者:张博周平坤黄琼萍朱学良鄢秀敏更多>>
相关机构:沈阳农业大学军事医学科学院北京大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Author Correction: Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration被引量:3
《Cell Research》2021年第3期373-373,共1页Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 
This work was also supported by the Ministry of Science and Technology of China(2016YFA0100400);the Chinese Academy of Sciences(XDB39000000 and QYZDY-SSW-SMC031);Z.Z.is sponsored by the Youth Innovation Promotion Association(2017133)of the Chinese Academy of Sciences.
We apologize for the mistake of the fund information in the acknowledgements.The correct information is as follows.This correction does not affect the conclusion of the work.
关键词:Kinetics CORRECTION CONCLUSION 
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration被引量:8
《Cell Research》2020年第11期980-996,共17页Xuan Ming Zhuqiang Zhang Zhuoning Zou Cong Lv Qiang Dong Qixiang He Yangyang Yi Yingfeng Li Hailin Wang Bing Zhu 
This work was primarily supported by the National Natural Science Foundation of China(31530047);This work was also supported by the Ministry of Science and Technology of China(2016YFA0100400);the Chinese Academy of Sciences(XDB39000000 and QYZDYSSW-SMC031);Z.Z.is sponsored by the Youth Innovation Promotion Association(2017133)of the Chinese Academy of Sciences.
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell identity.Whether DNA methylation pattern in different genomic contexts can all be faithfully maintained is an open question.A ...
关键词:IMPAIRED aging kinetics 
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing被引量:1
《Cell Research》2020年第11期997-1008,共12页Morgane Macheret Rahul Bhowmick Katarzyna Sobkowiak Laura Padayachy Jonathan Mailler Ian D.Hickson Thanos D.Halazonetis 
This study was supported by grants from the Swiss National Science Foundation(160734)to T.D.H.and from the Danish National Research Foundation(DNRF115);the Nordea Foundation,and the Novo Nordisk Foundation to I.D.H.
DNA replication stress,a feature of human cancers,often leads to instability at specific genomic loci,such as the common fragile sites(CFSs).Cells experiencing DNA replication stress may also exhibit mitotic DNA synth...
关键词:SYNTHESIS SITES REPAIR 
Genome-wide high-resolution mapping of mitotic DNA synthesis sites and common fragile sites by direct sequencing被引量:1
《Cell Research》2020年第11期1009-1023,共15页Fang Ji Hongwei Liao Sheng Pan Liujian Ouyang Fang Jia Zaiyang Fu Fengjiao Zhang Xinwei Geng Xinming Wang Tingting Li Shuangying Liu Madiha Zahra Syeda Haixia Chen Wen Li Zhihua Chen Huahao Shen Songmin Ying 
This work was supported by grants to Songmin Ying from the Ministry of Science and Technology of China(2016YFA0100301);the National Natural Science Foundation of China(81870007,81920108001);the Zhejiang Provincial Natural Science Foundation(LD19H160001);the Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents(2016-63).
Common fragile sites(CFSs)are genomic loci prone to the formation of breaks or gaps on metaphase chromosomes.They are hotspots for chromosome rearrangements and structural variations,which have been extensively implic...
关键词:synthesis RESOLUTION BRIDGING 
Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells被引量:7
《Cell Research》2018年第5期544-555,共12页Chen Qi Xin Wang Zhirong Shen She Chen Hong Yu Noelle Williams Gelin Wang 
The commonly used antimitotic chemotherapeutic agents such as taxol and vinblastine arrest cell cycle progression by disrupting mitotic spindles, and cause cancer cells to undergo apoptosis through 'mitotic catastro...
关键词:APOPTOSIS 有丝分裂 死亡受体 房间 癌症 激活 TAXOL 代理人 
Cortical neurons gradually attain a post-mitotic state
《Cell Research》2016年第9期1033-1047,共15页Froylan Calderon de Anda Ram Madabhushi Damien Rei Jia Meng Johannes Graff Omer Durak Konstantinos Meletis Melanie Richter Birgit Schwanke Alison Mungenast Li-Huei Tsai 
Once generated, neurons are thought to permanently exit the cell cycle and become irreversibly differentiated. However, neither the precise point at which this post-mitotic state is attained nor the extent of its irre...
关键词:post-mitotic neuronal state cell cycle IONOMYCIN calcium influx RNA-seq channel rhodopsin 
A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer被引量:1
《Cell Research》2016年第8期946-962,共17页Daniel Dominguez Yi-Hsuan Tsai Nicholas Gomez Deepak Kumar Jha Ian Davis Zefeng Wang 
Progression through the cell cycle is largely dependent on waves of periodic gene expression, and the regulatory networks for these transeriptome dynamics have emerged as critical points of vulnerability in various as...
关键词:cell cycle periodic transcriptome epigenetic regulation mitotic trait 
Cyclin B1: conductor of mitotic symphony orchestra被引量:2
《Cell Research》2008年第2期218-220,共3页Huijuan Yu Xuebiao Yao 
The inheritance of human genome through mitosis is precisely regulated by a series of tightly orchestrated events such as chromosome condensation, bi-orientated spindle formation, chromosome congression,
关键词:细胞周期蛋白B1 交响乐 管弦乐队 有丝分裂 导体 
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