MITOTIC

作品数:63被引量:108H指数:6
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相关领域:生物学医药卫生更多>>
相关作者:张博周平坤黄琼萍朱学良鄢秀敏更多>>
相关机构:沈阳农业大学军事医学科学院北京大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Human KIAA1018/FAN1 nuclease is a new mitotic substrate of APC/C^(Cdh1)
《Chinese Journal of Cancer》2012年第9期440-448,共9页Fenju Lai Kaishun Hu Yuanzhong Wu Jianjun Tang Yi Sang Jingying Cao Tiebang Kang 
supported by grants from Natural Science Foundation of Guangdong Province(No.10251008901000000 toT.K.);Ph.D.Program Foundation of Ministry of Education of China(No.20100171110079toT.K.);China Post doctoral Science Foundation(No.20110490966)
A recently identified protein, FAN1 (FANCD2-associated nuclease 1, previously known as KIAA1018), is a novel nuclease associated with monoubiquitinated FANCD2 that is required for cellular resistance against DNA inter...
关键词:有丝分裂过程 核酸酶 基板 蛋白质含量 人力 DNA链 ICL 泛素化 
Functional switching of ATM:sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells
《Chinese Journal of Cancer》2012年第8期364-372,共9页Yan Li Hua Xiong Da-Qing Yang 
supported by a research grant from A-T Children's Project (ATCP) received by Da-Qing Yang
Ataxia-telangiectasia(A-T) is an autosomal recessive disorder characterized by cerebellar ataxia and oculocutaneous telangiectasias.The gene mutated in this disease,ATM(A-T,mutated),encodes a 370-kDa Ser/Thr protein k...
关键词:神经元样细胞 DNA损伤 细胞增殖 ATM AKT SH-SY5Y细胞 人类 有丝分裂 
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