V. ACKNOWLEDGMENTS This work was supported by the National Natural Science Foundation of China (No.11074233) the National Basic Research Program of China (No.2012CB215405), and the Specialized Research Fund for the Doctoral Program of Higher Education (No.20113402110038).
The conformations for leucine (Leu) hydrated with one to three water molecules, Leu-(H2O)n (n=1-3), were carefully searched by considering the trial structures generated by all possible combinations of rotamers ...