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LncRNA PVT1对弥漫大B细胞淋巴瘤细胞活性的影响及其机制
《青岛大学学报（医学版）》2024年第3期381-387,共7页路晓辉 李文永 王孟林 陈香莉 
河南省医学科技攻关计划联合共建项目(LHGJ20191341)。
目的 探究长链非编码RNA(LncRNA)浆细胞瘤变体异位基因1(PVT1)对弥漫大B细胞淋巴瘤(DLBCL)细胞生物学行为的影响,并分析其潜在机制。方法 收集41例DLBCL病人和15例淋巴结反应性增生(RLH)病人的组织标本,体外培养人正常B淋巴细胞GM12878...
关键词：淋巴瘤 大B细胞 弥漫性 RNA 长链非编码 浆细胞瘤变体异位基因1 miR-145-5p 细胞周期蛋白依赖激酶6 
LncRNA NKILA inhibits HBV replication by repressing NF-κB signalling activation
《Virologica Sinica》2024年第1期44-55,共12页Xi Zhang Yuanyuan Li Chen Huan Yubao Hou Rujia Liu Hongyun Shi Peng Zhang Baisong Zheng Yingchao Wang Hong Wang Wenyan Zhang 
supported in part by funding from the National Key R&D Program of China(2021YFC2301900,2021YFC2301903,and 2021YFC2301904);National Natural Science Foundation of China(81672004 and 81930062 to WZ;81801993 to HW);Science and Technology Department of Jilin Province(20190101003JH,20190201272JC,20200201331JC,and 20200201422JC);the Key Laboratory of Molecular Virology,Jilin Province(20102209);supported by Fundamental Research Funds for Central Universities.
Hepatitis B virus(HBV)infection results in liver cirrhosis and hepatocellular carcinoma(HCC).HBx/nuclear factor(NF)-κB pathway plays a role in HBV replication.However,whether NF-κB-interacting long noncoding RNA(NKI...
关键词：LncRNA NF-κB-interacting longnoncoding RNA(NKILA) NF-ĸB signalling ChronichepatitisBvirus(HBV) Viral replication HBX 
Huangqi Decoction,a compound Chinese herbal medicine,inhibits the proliferation and activation of hepatic stellate cells by regulating the long noncoding RNA-C18orf26-1/microRNA-663a/transforming growth factor-βaxis被引量：5
《Journal of Integrative Medicine》2023年第1期47-61,共15页Ben-sheng Dong Fu-qun Liu Wen-na Yang Xiao-dong Li Miao-juan Shi Mao-rong Li Xiu-li Yan Hui Zhang 
supported by grants from the National Natural Science Foundation of China (No.82074101 and No.81773979);Shanghai Municipal Health Commission (No.202040486)
Objective Huangqi Decoction(HQD),a classical traditional Chinese medicine formula,has been used as a valid treatment for alleviating liver fibrosis;however,the underlying molecular mechanism is still unknown.Although ...
关键词：Longnoncoding RNA-C18orf26-1 MicroRNA-663a Transforming growth factor-β Hepatic stellate cells Huangqi Decoction 
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