Association of Early-Life Famine Exposure with Metabolic Dysfunction-Associated Fatty Liver Disease and Fibrosis in Adulthood  

作　　者：WEI Ran QI Hong Yan LIN Lin ZHU Yuan Yue ZHANG Yi ZHANG Jie WU Xue Yan HU Chun Yan WANG Shuang Yuan LIN Hong XU Yu XU Min BI Yu Fang WANG Wei Qing LU Jie Li NING Guang CHEN Yu Hong 

机构地区：[1]Department of Endocrine and Metabolic Diseases,Shanghai Institute of Endocrine and Metabolic Diseases,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China [2]Shanghai National Clinical Research Center for Metabolic Diseases,Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China,Shanghai National Center for Translational Medicine,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China

出　　处：《Biomedical and Environmental Sciences》2022年第6期558-562,共5页生物医学与环境科学（英文版）

基　　金：supported by the Shanghai Science and Technology Commission[19411964200];National Natural Science Foundation of China[81930021,81970728,81970691,82170819,and 21904084];Shanghai Outstanding Academic Leaders Plan[20XD1422800];Chinese Academy of Medical Sciences[2018PT32017 and 2019PT330006];Shanghai Medical and Health Development Foundation[DMRFP_I_01];Clinical Research Plan of SHDC[SHDC2020CR3064B];Science and Technology Committee of Shanghai[20Y11905100]

摘　　要：Nonalcoholic fatty liver disease(NAFLD)is known for its insidious onset and chronic nature,which have jeopardized the health and life of 29.2%of adults in China[1].In 2020,metabolic dysfunctionassociated fatty liver disease(MAFLD),a more accurate nomenclature to replace NAFLD,was put forward in an international consensus of experts involving 22 countries[2].In China,at least 300 million people will suffer from MAFLD by 2030,which will be a heavy burden on national health[3].

关 键 词：NAFLD Liver METABOLIC 

分 类 号：R575.5[医药卫生—消化系统]