Hepatobiliary Tumors: Update on Diagnosis and Management  

作　　者：Ghassan Kabbach Hussein A Assi George Bolotin Michael Schuster Hwa Jeong Lee Micheal Tadros 

机构地区：Department of internal medicine, Albany medical center, Albany, NY, USA Department of radiology, Albany medical center, Albany, NY, USA Department of pathology, Albany medical center, Albany, NY, USA Department of internal medicine, Division of gastroenterology, Albany medical center, Albany, NY, USA

出　　处：《Journal of Clinical and Translational Hepatology》2015年第3期169-181,共13页临床与转化肝病杂志（英文版）

摘　　要：Tumors of the liver and biliary tree,mainly hepatocellular carcinoma and cholangiocarcinoma,are the second leading cause of cancer related death worldwide and the sixth leading cause of cancer related death among men in developed countries.Recent developments in biomarkers and imaging modalities have enhanced early detection and accurate diagnosis of these highly fatal malignancies.These advances include serological testing,micro-ribonucleic acids,fluorescence in situ hybridization,contrast-enhanced ultrasound,and hepatobiliary-phase magnetic resonance imaging.In addition,there have been major developments in the surgical and nonsurgical management of these tumors,including expansion of the liver transplantation criteria,new locoregional treatments,and molecularly targeted therapies.In this article,we review various types of hepatobiliary tumors and discuss new developments in their diagnosis and management.Tumors of the liver and biliary tree,mainly hepatocellular carcinoma and cholangiocarcinoma,are the second leading cause of cancer related death worldwide and the sixth leading cause of cancer related death among men in developed countries.Recent developments in biomarkers and imaging modalities have enhanced early detection and accurate diagnosis of these highly fatal malignancies.These advances include serological testing,micro-ribonucleic acids,fluorescence in situ hybridization,contrast-enhanced ultrasound,and hepatobiliary-phase magnetic resonance imaging.In addition,there have been major developments in the surgical and nonsurgical management of these tumors,including expansion of the liver transplantation criteria,new locoregional treatments,and molecularly targeted therapies.In this article,we review various types of hepatobiliary tumors and discuss new developments in their diagnosis and management.

关 键 词：Hepatobiliary tumors Hepatocellular carcinoma CHOLANGIOCARCINOMA Liver cancer Diagnosis Treatment Management 

分 类 号：R73[医药卫生—肿瘤]