The role of APOBEC3B in the development of hepatocellular carcinoma should be investigated with the consideration of hepatitis B virus evolution  

作　　者：Wen-Bin Liu Guang-Wen Cao 

机构地区：[1]Department of Epidemiology, Second Military Medical University, Shanghai 200433, China

出　　处：《Hepatoma Research》2019年第8期7-10,共4页肝癌研究（英文版）

基　　金：This work was supported by grant(2015CB554006)from the National Key Basic Research Program of China(GC)

摘　　要：The chronic infection of hepatitis B virus(HBV)is the major cause of hepatocellular carcinoma(HCC)globally[1].In Eastern China,chronic HBV infection contributes to 87.5%of HCC whereas chronic hepatitis C virus(HCV)infection contributes to 1.7%[2].The mortality of HCC has increased in Europe and America over recent decades[3].Although the infection of HCV is the leading cause of HCC in most European and American countries,the contribution of HBV is increasing possibly due to immigration[3].

关 键 词：INFECTION HEPATOCELLULAR HEPATITIS 

分 类 号：R73[医药卫生—肿瘤]