A review of Acanthamoeba keratitis in the Middle East and Iran  

作　　者：Mohammad Hossein Feiz Haddad Azar Shokri Habib Habibpour Seyede Manizhe Heidar Nejadi 

机构地区：[1]Infectious and Tropical Diseases Research Center,Health Research Institute,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran [2]Department of Parasitology,Faculty of Medicine,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran [3]Vector-borne Disease Research Center,North Khorasan University of Medical Sciences,Bojnurd,Iran [4]Student Research Committee,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran [5]Department of Parasitology,Faculty of Medicine,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran [6]Shoushtar Faculty of Medical Sciences,Shoushtar,Iran

出　　处：《Journal of Acute Disease》2019年第4期133-141,共9页急性病杂志（英文版）

摘　　要：Acanthamoeba keratitis, a vision-threatening disease, is caused by a free-living amoeba of genus Acanthamoeba. Amoeba is widely distributed all around the world. Several cases of Acanthamoeba keratitis have been reported from the Middle East and Iran as well. The infection is mainly caused by inappropriate use of contact lens;therefore, it is more common among lens wearers. The number of reported cases worldwide is increasing annually due to the increasing number of contact lens wearers for medical or cosmetic reasons. It is known that early diagnosis and treatment can reduce consequent damages, while the delay in these processes will deteriorate the vision. Nowadays contact lens wearing, surgery and use of corticosteroids are known to predispose to Acanthamoeba keratitis, and it was also believed that trauma was the main cause. Increasing public knowledge about Acanthamoeba infection, inquiring the history of patients, clinical signs and laboratory findings can be helpful to early diagnosis and better treatment. Regardless of the increasing knowledge of diagnosis and treatment, this disease is still a challenge. Considering the long curative time, and insufficient efficacy of available treatments, it seems that the prevention is more important than the treatment. This review aimed to explain Acanthamoeba keratitis in the Middle East and Iran from the aspects of epidemiology, diagnosis, and therapeutic treatment.

关 键 词：ACANTHAMOEBA KERATITIS DIAGNOSIS THERAPY MIDDLE EAST Iran 

分 类 号：R73[医药卫生—肿瘤]