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作 者:DONGMin
机构地区:[1]Danyang People's Hospital, Zhenjiang Jiangsu 212300, China
出 处:《外文科技期刊数据库(文摘版)医药卫生》2022年第6期067-070,共4页
摘 要:To investigate the application value of combined anlotinib and irinotecan in the clinical treatment of patients with advanced relapsed and refractory small cell lung cancer. Methods: The interval of subjects included in this study was from August 2020 to August 2021, and the included cases were all patients with advanced relapsed and refractory small cell lung cancer who were treated in our hospital during the above period, with a total of 90 cases. Patients were numbered 1-90 according to the order of admission, and patients numbered 1-45 were included in the control group, and patients in this group were treated with irinotecan. Patients numbered 46-90 were included in the study group. Patients in this group were treated with anlotinib regimen at the same time as the control group, and the prognostic indicators were analyzed to evaluate the intervention effect. Results: Compared between the two groups, the disease control rate of the study group was higher, P < 0.05;The serum indexes of the study group were lower, P < 0.05;The incidence of adverse reactions in the study group was lower, P < 0.05;The score of quality of life in the study group was higher, P < 0.05;The score of sleep quality in the study group was higher, P < 0.05. Conclusion: The combination of anlotinib and irinotecan as second-line therapy in the treatment of patients with relapsed and refractory small cell lung cancer can effectively control the progression of the disease, improve the serum indexes, and promote the improvement of the disease. It is recommended to be popularized and applied.
关 键 词:relapsed or refractory small cell lung cancer late stage anlotinib IRINOTECAN second-line treatm
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