Effect of Butylphthalide Sodium Chloride Combined with Argatroban on Neurological Function in Patients with Ischemic Stroke  

作　　者：JIANGMin 

机构地区：[1]Dingzhou People's Hospital, Dingzhou Hebei 073000, China

出　　处：《外文科技期刊数据库(文摘版)医药卫生》2022年第9期106-109,共4页

摘　　要：Objective: to explore the feasibility and effectiveness of butylphthalide sodium chloride combined with argatroban in the clinical treatment of patients with ischemic stroke. Methods: the study was conducted in a retrospective way. The period of case inclusion ranged from April 2021 to May 2022. Seventy patients with ischemic stroke in our hospital were selected and randomly divided into standardized groups. Among them, 33 cases were included in the control group and given conventional treatment with butylphthalide sodium chloride, while 37 cases in the observation group were given butylphthalide sodium chloride combined with argatroban;The total effective rate, neurological function, daily living ability, cognitive function, limb motor function, serum lipoprotein phospholipase A2(LP-PLA2), fibrinogen (FIB) and other indicators were observed and compared between the two groups. Results: (1) through the evaluation of the therapeutic effect of all subjects, the total therapeutic effect of the observation group was 97.2%, which was significantly better than that of the control group (P<0.05). (2) After receiving all the treatments, the life activities and the degree of nerve defect of the two groups of patients have changed significantly, and the difference is greater than that of the control group, and the change in the observation group is more significant (P < 0.05). (3) The cognitive function and limb movement function of the two groups of patients were improved after receiving all treatments. Compared with the control group, the cognitive function and limb movement function of the observation group were significantly higher than those of the control group(P<0.05). (4) Before the implementation of the treatment, the FIB and LP-PLA2 indexes of the two groups of patients were evaluated and compared, with no significant difference in level (P>0.05). after all the treatment, the FIB and LP-PLA2 values of the two groups of patients were evaluated, with each index showing a decrease, and each index of the observation

关 键 词：ischemic stroke butylphthalide sodium chloride ARGATROBAN neurological function daily living abi 

分 类 号：R74[医药卫生—神经病学与精神病学]