盐酸左氧氟沙星葡萄糖注射液细菌内毒素检查的方法学研究  

Study of bacterial eadotoxin test for levofloxacin hydrochloride and glucosin injection

作　　者：陈晓平 

机构地区：[1]湖州市药品检验所,浙江湖州313000

出　　处：《中国现代应用药学》2005年第z1期639-641,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的考察盐酸左氧氟沙星葡萄糖注射液的细菌内毒素检查的方法.方法按中国药典2000年版二部收载的细菌内毒素方法进行实验,并与热原检查法进行对比。结果盐酸左氧氟沙星葡萄糖注射液对鲎试剂的凝聚反应无干扰作用。结论本品可用细菌内毒素检查法替代热原检查法。OBJECTIVE To examine the method for testing bacterial endotoxin in levofloxacin hydrochloride and glucosin injection(LHGI).METHOD Bacterial endotoxin test in the Chinese pharmacopoeia 2000 was used,and compared with pyrogen test.RESULTS The test showed that no inteference of LHGI to TAL reagents.CONCLUSION A bacterial endotoxin test method was established and replace pyrogen test for this specimen.

关 键 词：盐酸左氧氟沙星注射液 鲎试剂 细菌内毒素 

分 类 号：R927.12[医药卫生—药学]