Pericardiocentesis with cisplatin for malignant pericardial effusion and tamponade  

作　　者：Takatsugu Oida Kenji Mimatsu Hiso Kano Atsushi Kawasaki Youichi Kuboi Nobutada Fukino Sadao Amano 

机构地区：[1]Department of Surgery,Social Insurance Yokohama Central Hospital [2]Department of Surgery,Nihon University School of Medicine

出　　处：《World Journal of Gastroenterology》2010年第6期740-744,共5页世界胃肠病学杂志（英文版）

摘　　要：AIM:To evaluate the role and outcome of pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer. METHODS:We retrospectively studied 7 patients who underwent pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer.After pericardiocentesis,we performed catheterization of the pericardial space under ultrasonogram guidance.Malignant etiology of the pericardial fluid was confirmed by cytological examination.Subsequently,cisplatin(10 mg in 20 mL normal saline) was instilled into the pericardial space. RESULTS:The mean total volume of the aspirated effusion fluid was 782±264 mL(range,400-1200 mL) . The drainage catheter was successfully removed in all patients,and the mean duration of pericardial drainagewas 7.7±2.7 d(range,5-13 d) .No fluid reaccumulation was observed.Mean survival time was 120±71 d(range,68-268 d) . CONCLUSION:Pericardiocentesis along with catheter drainage appears to be a safe and effective for pericardial malignant effusion and tamponade,and cisplatin instillation prevents recurrence.AIM:To evaluate the role and outcome of pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer. METHODS:We retrospectively studied 7 patients who underwent pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer.After pericardiocentesis,we performed catheterization of the pericardial space under ultrasonogram guidance.Malignant etiology of the pericardial f...

关 键 词：Malignant pericardial effusion Cardiac tamponade Esophageal cancer PERICARDIOCENTESIS CISPLATIN 

分 类 号：R730.5[医药卫生—肿瘤]