Controversies about the use of serological markers indiagnosis of in flammatory bowel disease  

作　　者：Xie, Qin Gan, Hua-Tian 

机构地区：[1]Sichuan Univ, Dept Geriatr, W China Hosp, Chengdu 610041, Sichuan, Peoples R China [2]Sichuan Univ, Dept Gastroenterol, W China Hosp, Chengdu 610041, Sichuan, Peoples R China

出　　处：《World Journal of Gastroenterology》2010年第2期279-280,共2页世界胃肠病学杂志（英文版）

摘　　要：The serological markers are increasingly used in diagnosis of inflammatory bowel disease(IBD).D-lactate and diamine oxidase are new indicators that can be used to reveal the damage to intestinal mucosa and permeability alteration in IBD.Although the two biological markers seem more sensitive,recent clinical trials and animal experiments have shown controversies about the use of them in diagnosis of IBD.Therefore, these markers should be interpreted cautiously and further prospective studies are needed to establish their clinical role in diagnosis of IBD.The serological markers are increasingly used in diagnosis of inflammatory bowel disease(IBD).D-lactate and diamine oxidase are new indicators that can be used to reveal the damage to intestinal mucosa and permeability alteration in IBD.Although the two biological markers seem more sensitive,recent clinical trials and animal experiments have shown controversies about the use of them in diagnosis of IBD.Therefore, these markers should be interpreted cautiously and further prospective studies are needed to es...

关 键 词：Inflammatory bowel diseases D-LACTATE Diamine oxidase Intestinal permeability DIAGNOSIS 

分 类 号：R574[医药卫生—消化系统]