D-LACTATE

作品数：12被引量：80H指数：5
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相关领域：医药卫生更多>>
相关作者：常晓李文波李军张文明白国昌更多>>
相关机构：郴州市第一人民医院中南大学新乡医学院第一附属医院福建医科大学更多>>
相关期刊：《Signal Transduction and Targeted Therapy》《World Journal of Emergency Medicine》《World Journal of Gastroenterology》《Journal of Nutritional Oncology》更多>>
相关基金：国家重点基础研究发展计划国家自然科学基金更多>>
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Synthesis and molecular recognition characteristics of a tetrapodal benzene cage
《Chinese Chemical Letters》2024年第8期240-244,共5页Caihong Mao Yanfeng He Xiaohan Wang Yan Cai Xiaobo Hu 
support by the National Natural Science Foundation of China(No.22101260);Natural Science Foundation of Zhejiang Province(No.LQ22B020001).
In this contribution,we describe the preparation and recognition characteristics of a novel tetrapodal benzene cage(1).The cage can express a wide recognition range without losing selectivity for the object of appropr...
关键词：Cage molecules Host-guest chemistry Multi-step organic synthesis d-Lactate recognition l-Asp recognition 
Biosensor-assisted CRISPRi high-throughput screening to identify genetic targets in Zymomonas mobilis for high d-lactate production
《Synthetic and Systems Biotechnology》2024年第2期242-249,共8页Qiqun Peng Weiwei Bao Binan Geng Shihui Yang 
This work was supported by the National Key Research and Development Program of China(2022YFA0911800);National Natural Science Foundation of China(CN)(21978071);the Key Science and Technology Innovation Project of Hubei Province(2021BAD001);the Innovation Base for Introducing Talents of Discipline of Hubei Province(2019BJH021);We also acknowledge the support from the State Key Laboratory of Biocatalysis and Enzyme Engineering.
Lactate is an important monomer for the synthesis of poly-lactate(PLA),which is a substitute for the petrochemical plastics.To achieve the goal of high lactate titer,rate,and yield for commercial production,efficient ...
关键词：D-LACTATE BIOSENSOR LldR Genome-wide CRISPRi FACS Zymomonas mobilis 
超早期EN联合乌司他丁治疗SAP对免疫功能、D-lactate、endotoxin的影响
《中文科技期刊数据库（全文版）医药卫生》2023年第11期44-47,共4页李军 
湖南省卫生健康委科研计划项目,项目名称:《超早期肠内营养联合乌司他丁治疗急性重症胰腺炎的作用机制探究及对免疫功能、乳酸、内毒素的影响》,项目编号:202210003702。
探讨分析急性重症胰腺炎(severe acute pancreatitis,SAP)患者采用超早期肠内营养(enteral nutrition, EN)联合乌司他丁治疗对免疫功能、D-lactate、endotoxin产生的影响效应。方法 本次研究时间节点为2022年1月—2022年12月,选择了在...
关键词：超早期肠内营养 急性重症胰腺炎 免疫功能 D-LACTATE ENDOTOXIN 
CDK7-YAP-LDHD axis promotes D-lactate elimination and ferroptosis defense to support cancer stem cell-like properties被引量：4
《Signal Transduction and Targeted Therapy》2023年第9期4346-4364,共19页Mengzhu Lv Ying Gong Xuesong Liu Yan Wang Qingnan Wu Jie Chen Qingjie Min Dongyu Zhao Xianfeng Li Dongshao Chen Di Yang Danna Yeerken Rui Liu Jinting Li Weimin Zhang Qimin Zhan 
This work was supported by the National Natural Science Foundation of China(81988101,82172930,81830086,and 81802780);Beijing Municipal Commission of Health and Family Planning Project(PXM2018_026279_000005);Beijing Nova Program(Z191100001119038);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-081);Funding by Major Program of Shenzhen Bay Laboratory(S201101004);Guangdong Basic and Applied Basic Research Foundation(2019B030302012);the Fund of“San-ming”Project of Medicine in Shenzhen(No.SZSM201812088);Suzhou Outstanding Talent Team Fund(ZXD2022003).
Reprogrammed cellular metabolism is essential for maintaining cancer stem cells(CSCs)state.Here,we report that mitochondrial D-lactate catabolism is a necessary initiating oncogenic event during tumorigenesis of esoph...
关键词：ESOPHAGEAL metabolism ELEVATED 
Value of combining the serum D-lactate, diamine oxidase, and endotoxin levels to predict gut-derived infections in cancer patients被引量：1
《Journal of Nutritional Oncology》2023年第2期101-106,共6页Shou-Mei Yang Xiao-Dan Zhang Huai-XingMa DanWu XingLiu Hao-Bin Yu Shi-Wei Li Wen-Jun Gao Wei-Wei Liu Su-Yi Li 
Objective:This is a retrospective observational cohort study.The objective of this retrospective observational cohort study was to evaluate the value of the combined serum D-lactic acid,diamine oxidase(DAO),and endoto...
关键词：Cancer Diamine oxidase D-Lactic acid ENDOTOXIN Gut-derived infection 
Fermentation characteristics of Megasphaera elsdenii J6 derived from pig feces on different lactate isomers被引量：1
《Journal of Integrative Agriculture》2016年第7期1575-1583,共9页JIANG Xiao-lin SU Yong ZHU Wei-yun 
funding from the National Basic Research Program of China (2013CB127603 and 2012CB124705);the National Natural Science Foundation of China (31572414 and 30901036);the Natural Science Foundation of Jiangsu Province, China (BK20130058)
D-Lactate-utilizing bacteria play important roles in maintaining the balance of gut lactate; however, studies on gut D-lactate-uti-lizing bacteria have been limited. This study aimed to isolate and identify D-lactate-...
关键词：D-lactate-utilizing bacteria Megasphaera elsdeni BUTYRATE PIG GUT 
Functional changes of intestinal mucosal barrier insurgically critical patients被引量：26
《World Journal of Emergency Medicine》2010年第3期205-208,共4页Yuan-yuanGuo Mu-linLiu Xian-di He Cong-qiao Jiang Rui-lin Liu 
BACKGROUND： The gut is capable of inducing multiple organ dysfunction syndrome （MODS）. In the diagnosis and treatment of critical ill patients, doctors should pay particular attention to the protection or recovery ...
关键词：Intestinal mucosal barrier ENDOTOXIN Diamine oxidase D-LACTATE Intestinal fatty-acid binding protein 
Controversies about the use of serological markers indiagnosis of in flammatory bowel disease被引量：9
《World Journal of Gastroenterology》2010年第2期279-280,共2页Xie, Qin Gan, Hua-Tian 
The serological markers are increasingly used in diagnosis of inflammatory bowel disease(IBD).D-lactate and diamine oxidase are new indicators that can be used to reveal the damage to intestinal mucosa and permeabilit...
关键词：Inflammatory bowel diseases D-LACTATE Diamine oxidase Intestinal permeability DIAGNOSIS 
Soluble intercellular adhesion molecule-1,D-lactate and diamine oxidase in patients with inflammatory bowel disease被引量：23
《World Journal of Gastroenterology》2009年第31期3916-3919,共4页Wei-Bing Song Yong-Hui Lv Zhen-Shu Zhang Ya-Nan Li Li-Ping Xiao Xin-Pei Yu Yuan-Yuan Wang Hong-Li Ji Li Ma 
AIM： To study the levels of serum soluble intercellular adhesion molecule-1 （sICAM-1）, plasma D-lactate and diamine oxidase （DAO） in patients with inflammatory bowel disease （IBD）, and the potential clinical si...
关键词：Inflammatory bowel diseases Intercellular adhesion molecule-1 D-LACTATE Diamine oxidase 
Effect of Lianshu preparation on lipopolysaccharide-induced diarrhea in rats被引量：7
《World Journal of Gastroenterology》2009年第16期2009-2015,共7页Jun Liu Rong Wan Xuan-Fu Xu Xing-Peng Wang Wen-Juan Yang Yu-Jing Xia Hua Liu Qian-Lin Yan De-Xin Yan Chuan-Yong Guo 
Supported by State Administration of Chinese Medicine,No.04-06LP24;Health Bureau of Shanghai,No.06ER14090;the Major State Basic Research Development Program of China "973 Program",No.2006CB504810
AIM： To investigate the effect of Lianshu preparation on lipopolysaccharide （LPS）-induced diarrhea in rats. METHODS： A diarrhea model was established in Sprague Dawley rats via injection of 1 mL of 30 mg/kg LPS. A...
关键词：Lianshu preparation LIPOPOLYSACCHARIDE DIARRHEA Nitrogen monoxide D-LACTATE 
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