巯基乙酸修饰金电极电化学发光行为的研究及其对盐酸硫必利的测定  

Study on electrochemical luminescence and determination of tiapride hydrochloride based on a mercaptoacetic acid modified gold electrode using Ru(bpy)_3^(2+) system

作　　者：李利军[1] 蔡卓[2] 高文燕[2] 李彦青[1] 胡大春[1] 

机构地区：[1]广西工学院生物与化学工程系,柳州545006 [2]广西大学化学化工学院,南宁530004

出　　处：《分析试验室》2010年第8期5-8,共4页Chinese Journal of Analysis Laboratory

基　　金：国家自然科学基金(20665001);桂科自(0832062)项目资助

摘　　要：在裸金电极上制备了巯基乙酸自组装膜修饰电极(MA/SAMs-Au/CME)。基于盐酸硫必利对联吡啶钌在该电极上的电化学及其发光行为的强烈增敏作用,建立起一种直接测定盐酸硫必利电致化学发光新方法。在最佳实验条件下,盐酸硫必利在1.0×10-4～1.0×10-7mol/L与相对发光强度呈线性关系,其线性回归方程I(强度)=27.169×106c+140.26,r2=0.9959,检出限(S/N=3)为5.11×10-9mol/L。连续测定1.0×10-5mol/L盐酸硫必利10次,发光强度的RSD值为1.8%。对样品进行回收率试验,回收率在94.1%～104.9%之间,RSD为4.5%(n=5)。A mercaptoacetic acid self-assembled monolayer gold electrode(abbreviated as MA/SAM-Au/CME) was prepared.Based on the enhancement of the electrochemical and ECL characteristics of Ru(bpy)32+ in the presence of tiapride hydrochloride,a new ECL method was established for the determination of tiapride hydrochloride at the modified electrode(MA/SAM-Au/CME) in this paper.Under the optimal experimental conditions,the ECL peak counts increased linearly with the concentration of tiapride hydrochloride in the range ...

关 键 词：巯基乙酸 化学修饰电极 盐酸硫必利 联吡啶钌 

分 类 号：R914[医药卫生—药物化学]