胎儿后尿道瓣膜产前评估与宫内治疗(附1例报道)  

Prenatal Assessment and Intrauterine Treatment of Fetal Posterior Urethral Valves (A Case Report)

作　　者：鲁云涯[1] 周祎[1] 陈涌珍[1] 李满超[1] 黄林环[1] 朱云晓[1] 石慧娟[1] 商梅娇[1] 黄爱兰[1] 方群[1] 

机构地区：[1]中山大学附属第一医院妇产科胎儿医学中心,广东广州510080

出　　处：《中国产前诊断杂志（电子版）》2012年第2期46-51,共6页Chinese Journal of Prenatal Diagnosis(Electronic Version)

基　　金：广东省国际合作项目(2010B050700006);广东省科技基础条件建设项目(2011B060300011)

摘　　要：后尿道瓣膜(PUV)是胎儿下尿路梗阻最常见的病因,产前超声主要表现为羊水过少、膀胱壁进行性增厚和"钥匙孔征",严重者可导致肾积水和输尿管扩张。确诊胎儿PUV后应评估胎儿的肾功能、膀胱功能,监测羊水量以及进行染色体核型分析。对羊水过少而肾功能良好的病例,可考虑宫内治疗,目前可行的方法有膀胱-羊膜腔分流术、胎儿膀胱镜下后尿道瓣膜消融术,但其治疗价值还有待进一步观察和分析。Posterior urethral valves(PUV) is the most common anomaly of fetal lower urinary tract obstruction.Prenatal ultrasound can present oligohydramnios,thick-walled bladder and the 'keyhole sign'.In severe cases,they result in hydronephrosis and ureteric dilatation.If diagnosed,We should assess renal function and bladder function of the fetus,examine the amniotic fluid volume and analyze the chromosomal karyotype.For those fetuses with normal renal function and oligohydramnios,intrauterine treatment can be provided,such as Vesico-amniotic Shunting and fetal cystoscopy PUV ablation,while the value of these approaches needs further investigation.

关 键 词：后尿道瓣膜 下尿路梗阻 产前诊断 宫内治疗 

分 类 号：R714.55[医药卫生—妇产科学]